YAJC_RICFE
ID YAJC_RICFE Reviewed; 142 AA.
AC Q4UKW4;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 2.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Sec translocon accessory complex subunit YajC;
GN Name=yajC; OrderedLocusNames=RF_0958;
OS Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX NCBI_TaxID=315456;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC VR-1525 / URRWXCal2;
RX PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA Parinello H., Claverie J.-M., Raoult D.;
RT "The genome sequence of Rickettsia felis identifies the first putative
RT conjugative plasmid in an obligate intracellular parasite.";
RL PLoS Biol. 3:1-12(2005).
CC -!- FUNCTION: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein
CC secretase/insertase is a supercomplex required for protein secretion,
CC insertion of proteins into membranes, and assembly of membrane protein
CC complexes. While the SecYEG complex is essential for assembly of a
CC number of proteins and complexes, the SecDF-YajC-YidC subcomplex
CC facilitates these functions. {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SUBUNIT: Part of the SecDF-YidC-YajC translocase complex. The SecDF-
CC YidC-YajC translocase forms a supercomplex with SecYEG, called the
CC holo-translocon (HTL). {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P0ADZ7}; Single-pass membrane protein
CC {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SIMILARITY: Belongs to the YajC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAY61809.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; CP000053; AAY61809.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_039595119.1; NC_007109.1.
DR AlphaFoldDB; Q4UKW4; -.
DR SMR; Q4UKW4; -.
DR STRING; 315456.RF_0958; -.
DR EnsemblBacteria; AAY61809; AAY61809; RF_0958.
DR KEGG; rfe:RF_0958; -.
DR eggNOG; COG1862; Bacteria.
DR HOGENOM; CLU_116157_0_0_5; -.
DR OrthoDB; 2082059at2; -.
DR Proteomes; UP000008548; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR003849; Preprotein_translocase_YajC.
DR PANTHER; PTHR33909; PTHR33909; 1.
DR Pfam; PF02699; YajC; 1.
DR PRINTS; PR01853; YAJCTRNLCASE.
DR SMART; SM01323; YajC; 1.
DR TIGRFAMs; TIGR00739; yajC; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Translocation; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..142
FT /note="Sec translocon accessory complex subunit YajC"
FT /id="PRO_0000282379"
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 142 AA; 15866 MW; AD1A1A5256FD3D1C CRC64;
MSANTQDNQA NNNDTIEIQE TEVVPVETNS LQSGLTSLTP MVLIFAVFYF LLLRPQEKRR
KEREKLVSEV KKGEEVLTNS GIYGIVTKVS ENDNNIEIEI AKDVRIKALK SAIVDITSRT
KEVAVKKENN KKDKKVSGAK SS