ID   YAJC_THEMA              Reviewed;         116 AA.
AC   Q9WZW3;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=Sec translocon accessory complex subunit YajC;
GN   Name=yajC; OrderedLocusNames=TM_0859;
OS   Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS   / MSB8).
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=243274;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8;
RX   PubMed=10360571; DOI=10.1038/20601;
RA   Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA   Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A.,
RA   Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA   Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F.,
RA   Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L.,
RA   Smith H.O., Venter J.C., Fraser C.M.;
RT   "Evidence for lateral gene transfer between Archaea and Bacteria from
RT   genome sequence of Thermotoga maritima.";
RL   Nature 399:323-329(1999).
CC   -!- FUNCTION: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein
CC       secretase/insertase is a supercomplex required for protein secretion,
CC       insertion of proteins into membranes, and assembly of membrane protein
CC       complexes. While the SecYEG complex is essential for assembly of a
CC       number of proteins and complexes, the SecDF-YajC-YidC subcomplex
CC       facilitates these functions. {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SUBUNIT: Part of the SecDF-YidC-YajC translocase complex. The SecDF-
CC       YidC-YajC translocase forms a supercomplex with SecYEG, called the
CC       holo-translocon (HTL). {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:P0ADZ7}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SIMILARITY: Belongs to the YajC family. {ECO:0000305}.
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DR   EMBL; AE000512; AAD35941.1; -; Genomic_DNA.
DR   PIR; D72325; D72325.
DR   RefSeq; NP_228668.1; NC_000853.1.
DR   RefSeq; WP_004080747.1; NZ_CP011107.1.
DR   AlphaFoldDB; Q9WZW3; -.
DR   SMR; Q9WZW3; -.
DR   STRING; 243274.THEMA_00340; -.
DR   EnsemblBacteria; AAD35941; AAD35941; TM_0859.
DR   KEGG; tma:TM0859; -.
DR   eggNOG; COG1862; Bacteria.
DR   InParanoid; Q9WZW3; -.
DR   OMA; GMEMIIM; -.
DR   Proteomes; UP000008183; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003849; Preprotein_translocase_YajC.
DR   PANTHER; PTHR33909; PTHR33909; 1.
DR   Pfam; PF02699; YajC; 1.
DR   PRINTS; PR01853; YAJCTRNLCASE.
DR   SMART; SM01323; YajC; 1.
DR   TIGRFAMs; TIGR00739; yajC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..116
FT                   /note="Sec translocon accessory complex subunit YajC"
FT                   /id="PRO_0000097035"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   116 AA;  12843 MW;  E2836793CA744EA3 CRC64;
     MPEIIYAAAP GASNGTTTTA TGGGWGSLLF MLIFFIAIFY FMIILPQRRR EKQFQQMISQ
     MKRGDTVVTI GGIVGKVIDI KKDTVKIKTA NSTELEITKR AISTVIKERS QENQEG