ID   YAJC_TREPA              Reviewed;         135 AA.
AC   P58007;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   27-APR-2001, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Sec translocon accessory complex subunit YajC;
GN   Name=yajC; OrderedLocusNames=TP_0409.1;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
RN   [2]
RP   IDENTIFICATION.
RA   Medigue C., Bocs S.;
RL   Unpublished observations (APR-2001).
CC   -!- FUNCTION: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein
CC       secretase/insertase is a supercomplex required for protein secretion,
CC       insertion of proteins into membranes, and assembly of membrane protein
CC       complexes. While the SecYEG complex is essential for assembly of a
CC       number of proteins and complexes, the SecDF-YajC-YidC subcomplex
CC       facilitates these functions. {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SUBUNIT: Part of the SecDF-YidC-YajC translocase complex. The SecDF-
CC       YidC-YajC translocase forms a supercomplex with SecYEG, called the
CC       holo-translocon (HTL). {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:P0ADZ7}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SIMILARITY: Belongs to the YajC family. {ECO:0000305}.
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DR   EMBL; AE000520; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P58007; -.
DR   STRING; 243276.TPANIC_0409a; -.
DR   eggNOG; COG1862; Bacteria.
DR   OMA; GMEMIIM; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003849; Preprotein_translocase_YajC.
DR   PANTHER; PTHR33909; PTHR33909; 1.
DR   Pfam; PF02699; YajC; 1.
DR   PRINTS; PR01853; YAJCTRNLCASE.
DR   SMART; SM01323; YajC; 1.
DR   TIGRFAMs; TIGR00739; yajC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..135
FT                   /note="Sec translocon accessory complex subunit YajC"
FT                   /id="PRO_0000097036"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          108..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   135 AA;  14788 MW;  9BFABCF00C0E5876 CRC64;
     MCPARSRMKT MPHRTLLQIT TANGGWIPPL AIGVVCLIFY LFVFAPNLRE QKRTQALIKN
     IKKGDPVVTI GGIHGVVSVV REHSLVIKVN EHGTLEVSRS AIARINDRRG VSNPKTDCDS
     KPGVPLTGVD KEIAR