ID   YAJD_ECOLI              Reviewed;         115 AA.
AC   P0AAQ2; P19678; P77666; Q2MC16;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Putative HNH nuclease YajD;
DE            EC=3.1.-.-;
GN   Name=yajD; OrderedLocusNames=b0410, JW0400;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=2170107; DOI=10.1002/j.1460-2075.1990.tb07519.x;
RA   Gardel C., Johnson K., Jacq A., Beckwith J.;
RT   "The secD locus of E.coli codes for two membrane proteins required for
RT   protein export.";
RL   EMBO J. 9:3209-3216(1990).
RN   [2]
RP   ERRATUM OF PUBMED:2170107.
RX   PubMed=2249673; DOI=10.1002/j.1460-2075.1990.tb07645.x;
RA   Gardel C., Johnson K., Jacq A., Beckwith J.;
RL   EMBO J. 9:4205-4206(1990).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RA   Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA   Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA   Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT   "Sequence of minutes 4-25 of Escherichia coli.";
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SIMILARITY: Belongs to the HNH nuclease family. {ECO:0000305}.
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DR   EMBL; X56175; CAA39636.1; -; Genomic_DNA.
DR   EMBL; U82664; AAB40166.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC73513.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76190.1; -; Genomic_DNA.
DR   PIR; B64770; B64770.
DR   RefSeq; NP_414944.1; NC_000913.3.
DR   RefSeq; WP_000974813.1; NZ_STEB01000007.1.
DR   AlphaFoldDB; P0AAQ2; -.
DR   BioGRID; 4262189; 13.
DR   IntAct; P0AAQ2; 11.
DR   STRING; 511145.b0410; -.
DR   jPOST; P0AAQ2; -.
DR   PaxDb; P0AAQ2; -.
DR   PRIDE; P0AAQ2; -.
DR   EnsemblBacteria; AAC73513; AAC73513; b0410.
DR   EnsemblBacteria; BAE76190; BAE76190; BAE76190.
DR   GeneID; 66671291; -.
DR   GeneID; 945051; -.
DR   KEGG; ecj:JW0400; -.
DR   KEGG; eco:b0410; -.
DR   PATRIC; fig|511145.12.peg.426; -.
DR   EchoBASE; EB1089; -.
DR   eggNOG; COG1403; Bacteria.
DR   HOGENOM; CLU_136125_1_0_6; -.
DR   InParanoid; P0AAQ2; -.
DR   OMA; CHDNEHQ; -.
DR   PhylomeDB; P0AAQ2; -.
DR   BioCyc; EcoCyc:EG11097-MON; -.
DR   PRO; PR:P0AAQ2; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd00085; HNHc; 1.
DR   InterPro; IPR002711; HNH.
DR   InterPro; IPR003615; HNH_nuc.
DR   Pfam; PF01844; HNH; 1.
DR   SMART; SM00507; HNHc; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Nuclease; Reference proteome.
FT   CHAIN           1..115
FT                   /note="Putative HNH nuclease YajD"
FT                   /id="PRO_0000168606"
FT   DOMAIN          27..75
FT                   /note="HNH"
FT   CONFLICT        109..115
FT                   /note="AMMNKKK -> G (in Ref. 1; CAA39636)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   115 AA;  13364 MW;  04D99E2E3FBAA0C7 CRC64;
     MAIIPKNYAR LESGYREKAL KIYPWVCGRC SREFVYSNLR ELTVHHIDHD HTNNPEDGSN
     WELLCLYCHD HEHSKYTEAD QYGTTVIAGE DAQKDVGEAK YNPFADLKAM MNKKK