ID   YAJD_SALTY              Reviewed;         115 AA.
AC   P0A1S8; P40777;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Putative HNH nuclease YajD;
DE            EC=3.1.-.-;
GN   Name=yajD; OrderedLocusNames=STM0411;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=9043137; DOI=10.1099/00221287-143-2-603;
RA   Nieweg A., Bremer E.;
RT   "The nucleoside-specific Tsx channel from the outer membrane of Salmonella
RT   typhimurium, Klebsiella pneumoniae and Enterobacter aerogenes: functional
RT   characterization and DNA sequence analysis of the tsx genes.";
RL   Microbiology 143:603-615(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- SIMILARITY: Belongs to the HNH nuclease family. {ECO:0000305}.
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DR   EMBL; Z26657; CAA81400.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL19365.1; -; Genomic_DNA.
DR   PIR; S49161; S49161.
DR   RefSeq; NP_459406.1; NC_003197.2.
DR   RefSeq; WP_000974818.1; NC_003197.2.
DR   AlphaFoldDB; P0A1S8; -.
DR   STRING; 99287.STM0411; -.
DR   PaxDb; P0A1S8; -.
DR   EnsemblBacteria; AAL19365; AAL19365; STM0411.
DR   GeneID; 1251930; -.
DR   KEGG; stm:STM0411; -.
DR   PATRIC; fig|99287.12.peg.438; -.
DR   HOGENOM; CLU_136125_1_0_6; -.
DR   OMA; CHDNEHQ; -.
DR   PhylomeDB; P0A1S8; -.
DR   BioCyc; SENT99287:STM0411-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd00085; HNHc; 1.
DR   InterPro; IPR002711; HNH.
DR   InterPro; IPR003615; HNH_nuc.
DR   Pfam; PF01844; HNH; 1.
DR   SMART; SM00507; HNHc; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Nuclease; Reference proteome.
FT   CHAIN           1..115
FT                   /note="Putative HNH nuclease YajD"
FT                   /id="PRO_0000168611"
FT   DOMAIN          27..75
FT                   /note="HNH"
FT   CONFLICT        109..115
FT                   /note="AMMNKKK -> R (in Ref. 1; CAA81400)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   115 AA;  13307 MW;  55BF52BE5150EB2C CRC64;
     MAIIPKNYAR LESGYREKAL KLFPWVCGRC SREFVYSNLR ELTVHHIDHD HTNNPEDGSN
     WELLCLYCHD HEHSKYTEAD QYGSTVIAGE DAQKDVGEAT YNPFADLKAM MNKKK