YAO6_SCHPO
ID YAO6_SCHPO Reviewed; 455 AA.
AC Q10085;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Uncharacterized transporter C11D3.06;
GN ORFNames=SPAC11D3.06;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000305}.
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DR EMBL; CU329670; CAA92307.1; -; Genomic_DNA.
DR PIR; T37517; T37517.
DR RefSeq; NP_592803.1; NM_001018203.2.
DR AlphaFoldDB; Q10085; -.
DR SMR; Q10085; -.
DR STRING; 4896.SPAC11D3.06.1; -.
DR iPTMnet; Q10085; -.
DR PaxDb; Q10085; -.
DR PRIDE; Q10085; -.
DR EnsemblFungi; SPAC11D3.06.1; SPAC11D3.06.1:pep; SPAC11D3.06.
DR GeneID; 2542994; -.
DR KEGG; spo:SPAC11D3.06; -.
DR PomBase; SPAC11D3.06; -.
DR VEuPathDB; FungiDB:SPAC11D3.06; -.
DR eggNOG; KOG1347; Eukaryota.
DR HOGENOM; CLU_012893_1_2_1; -.
DR InParanoid; Q10085; -.
DR OMA; EFWILLK; -.
DR PhylomeDB; Q10085; -.
DR Reactome; R-SPO-425366; Transport of bile salts and organic acids, metal ions and amine compounds.
DR PRO; PR:Q10085; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0000329; C:fungal-type vacuole membrane; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR CDD; cd13132; MATE_eukaryotic; 1.
DR InterPro; IPR045069; MATE_euk.
DR InterPro; IPR002528; MATE_fam.
DR Pfam; PF01554; MatE; 2.
DR TIGRFAMs; TIGR00797; matE; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..455
FT /note="Uncharacterized transporter C11D3.06"
FT /id="PRO_0000164257"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 236..256
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 280..300
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 309..329
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 343..363
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 381..401
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 405..425
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 455 AA; 49086 MW; FF41087BC6405327 CRC64;
MGRPLTEVKY LLINSAPVIL GYALQNSLQT SSVIVTGRLG PSELSVAAFA YMFAMSTGWL
IALGGTTAFD TLGSNLWGAG KKQELGILLQ TGFIVLSILY LPICLVWWYS KPILIFLHQT
PELAEASQKF LRYLIPGGLG YVCFELLKKF LQTQEITRAG SYILLVTSPL NVALNFLLVH
YYGLGLKGAP LATGLSYWLS FILLTQYAKY VKGAEAWNGW NKRCLENFGP FVKLSLLGIV
MVGTEWWAFE IVALVAGKLG AVPLAAQSVI MTTDQLLNTI PFGLGIITSN RVAYYLGAGL
PDNASLTAKV AAIVGVAVGS VIMITMIAVR NIYGRIFTND PDVIQLVALV MPLVAAFQIS
DSLNGTMGGA LRGTGRQKVG AIVNITAYYL FALPLGIYLA FHGKGLVGLW IGQVIALSIV
GILELKIVMA TDWISQSRKA ISRFGDSSEL TALLN
