YAO_ARATH
ID YAO_ARATH Reviewed; 504 AA.
AC Q9M0V4;
DT 27-MAY-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 145.
DE RecName: Full=U3 snoRNP-associated protein-like YAO {ECO:0000305};
GN Name=YAO {ECO:0000303|PubMed:20699009};
GN OrderedLocusNames=At4g05410 {ECO:0000312|Araport:AT4G05410};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE,
RP AND DISRUPTION PHENOTYPE.
RX PubMed=20699009; DOI=10.1186/1471-2229-10-169;
RA Li H.J., Liu N.Y., Shi D.Q., Liu J., Yang W.C.;
RT "YAO is a nucleolar WD40-repeat protein critical for embryogenesis and
RT gametogenesis in Arabidopsis.";
RL BMC Plant Biol. 10:169-169(2010).
CC -!- FUNCTION: Component of a nucleolar small nuclear ribonucleoprotein
CC particle (snoRNP) thought to participate in the processing and
CC modification of pre-ribosomal RNA (By similarity). Essential for
CC embryogenesis. Plays a critical role in embryo sac development and
CC gametic cell fate. Required for the correct positioning of the first
CC division plane of zygote. May function during early embryogenesis
CC (PubMed:20699009). {ECO:0000250|UniProtKB:O43818,
CC ECO:0000269|PubMed:20699009}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:20699009}.
CC -!- TISSUE SPECIFICITY: Expressed in tissues with active in cell division
CC such as shoot apexes, root tips, lateral root primordia, embryos,
CC endosperm, pollen grains and embryo sacs.
CC {ECO:0000269|PubMed:20699009}.
CC -!- DEVELOPMENTAL STAGE: Strongly expressed in early embryos and endosperm,
CC but very weakly in globular embryos and further embryo developmental
CC stages. {ECO:0000269|PubMed:20699009}.
CC -!- DISRUPTION PHENOTYPE: Embryonic lethality when homozygous.
CC {ECO:0000269|PubMed:20699009}.
CC -!- SIMILARITY: Belongs to the WD repeat RRP9 family. {ECO:0000305}.
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DR EMBL; AL161503; CAB81083.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82516.1; -; Genomic_DNA.
DR EMBL; AY099817; AAM20668.1; -; mRNA.
DR EMBL; BT000325; AAN15644.1; -; mRNA.
DR PIR; A85068; A85068.
DR RefSeq; NP_192450.1; NM_116780.3.
DR AlphaFoldDB; Q9M0V4; -.
DR SMR; Q9M0V4; -.
DR STRING; 3702.AT4G05410.1; -.
DR iPTMnet; Q9M0V4; -.
DR PaxDb; Q9M0V4; -.
DR PRIDE; Q9M0V4; -.
DR ProteomicsDB; 228663; -.
DR EnsemblPlants; AT4G05410.1; AT4G05410.1; AT4G05410.
DR GeneID; 825889; -.
DR Gramene; AT4G05410.1; AT4G05410.1; AT4G05410.
DR KEGG; ath:AT4G05410; -.
DR Araport; AT4G05410; -.
DR TAIR; locus:2115984; AT4G05410.
DR eggNOG; KOG0299; Eukaryota.
DR HOGENOM; CLU_014017_1_1_1; -.
DR InParanoid; Q9M0V4; -.
DR OMA; MYRAPAS; -.
DR OrthoDB; 948159at2759; -.
DR PhylomeDB; Q9M0V4; -.
DR PRO; PR:Q9M0V4; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9M0V4; baseline and differential.
DR Genevisible; Q9M0V4; AT.
DR GO; GO:0080008; C:Cul4-RING E3 ubiquitin ligase complex; ISS:TAIR.
DR GO; GO:0005730; C:nucleolus; IDA:TAIR.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR GO; GO:0060321; P:acceptance of pollen; IMP:TAIR.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0009553; P:embryo sac development; IMP:TAIR.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR039241; Rrp9-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19865; PTHR19865; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding;
KW rRNA processing; WD repeat.
FT CHAIN 1..504
FT /note="U3 snoRNP-associated protein-like YAO"
FT /id="PRO_0000433090"
FT REPEAT 159..198
FT /note="WD 1"
FT /evidence="ECO:0000255"
FT REPEAT 220..259
FT /note="WD 2"
FT /evidence="ECO:0000255"
FT REPEAT 262..301
FT /note="WD 3"
FT /evidence="ECO:0000255"
FT REPEAT 304..342
FT /note="WD 4"
FT /evidence="ECO:0000255"
FT REPEAT 344..382
FT /note="WD 5"
FT /evidence="ECO:0000255"
FT REPEAT 413..452
FT /note="WD 6"
FT /evidence="ECO:0000255"
FT REPEAT 456..496
FT /note="WD 7"
FT /evidence="ECO:0000255"
FT REGION 1..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 504 AA; 56519 MW; C6481E5C81D46104 CRC64;
MKYNNEKKKG GSFKRGGKKG SNERDPFFEE EPKKRRKVSY DDDDIESVDS DAEENGFTGG
DEDGRRVDGE VEDEDEFADE TAGEKRKRLA EEMLNRRREA MRREREEADN DDDDDEDDDE
TIKKSLMQKQ QEDSGRIRRL IASRVQEPLS TDGFSVIVKH RRSVVSVALS DDDSRGFSAS
KDGTIMHWDV SSGKTDKYIW PSDEILKSHG MKLREPRNKN HSRESLALAV SSDGRYLATG
GVDRHVHIWD VRTREHVQAF PGHRNTVSCL CFRYGTSELY SGSFDRTVKV WNVEDKAFIT
ENHGHQGEIL AIDALRKERA LTVGRDRTML YHKVPESTRM IYRAPASSLE SCCFISDNEY
LSGSDNGTVA LWGMLKKKPV FVFKNAHQDI PDGITTNGIL ENGDHEPVNN NCSANSWVNA
VATSRGSDLA ASGAGNGFVR LWAVETNAIR PLYELPLTGF VNSLAFAKSG KFLIAGVGQE
TRFGRWGCLK SAQNGVAIHP LRLA
