ID   YARA_PROST              Reviewed;         282 AA.
AC   P46117;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator in aarA 3'region;
OS   Providencia stuartii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Providencia.
OX   NCBI_TaxID=588;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PR50;
RX   PubMed=8051030; DOI=10.1128/jb.176.16.5140-5144.1994;
RA   Rather P.N., Orosz E.;
RT   "Characterization of aarA, a pleiotrophic negative regulator of the 2'-N-
RT   acetyltransferase in Providencia stuartii.";
RL   J. Bacteriol. 176:5140-5144(1994).
RN   [2]
RP   IDENTIFICATION.
RA   Robison K.;
RL   Unpublished observations (JUL-1995).
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DR   EMBL; L28755; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P46117; -.
DR   SMR; P46117; -.
DR   STRING; 588.BGK56_18960; -.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   CDD; cd05013; SIS_RpiR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR000281; HTH_RpiR.
DR   InterPro; IPR035472; RpiR-like_SIS.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF01418; HTH_6; 1.
DR   Pfam; PF01380; SIS; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF53697; SSF53697; 1.
DR   PROSITE; PS51071; HTH_RPIR; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..282
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   in aarA 3'region"
FT                   /id="PRO_0000068628"
FT   DOMAIN          4..80
FT                   /note="HTH rpiR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00390"
FT   DOMAIN          125..265
FT                   /note="SIS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00797"
FT   DNA_BIND        40..59
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00390"
SQ   SEQUENCE   282 AA;  31531 MW;  B6DB79BC7EF43075 CRC64;
     MGMSTLTSKL ESLLNRGKGT EQRLARFLLD SRDNFVAMNV AELAQAAGVS SASVIRFTRQ
     MGYRGYSDFK VDYLSDEKQY KAESLSGSLN PYDDTEQIIA KSGQMFITAI EKSLELLDPN
     TMDEIAQKIV EAKRIVLFGV GTSAIVAYDI FYKLIRVNKY ALFSPDLHVQ LSYSSNVDAD
     DLVIAITAKG NTPDINHMLK LANKKGCSTI VLTRFGQDEA VRLADLVLPY FYDEQLFQTG
     VITPQVLQMV VFDTLFFKYL TLTNEDVVLA LQKEREAIIQ LG