YAS8_SCHPO
ID YAS8_SCHPO Reviewed; 563 AA.
AC Q10144;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Uncharacterized transcriptional regulatory protein C3H8.08c;
GN ORFNames=SPAC3H8.08c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; CU329670; CAA93165.1; -; Genomic_DNA.
DR PIR; T38766; T38766.
DR RefSeq; NP_593001.1; NM_001018400.2.
DR AlphaFoldDB; Q10144; -.
DR BioGRID; 280050; 13.
DR STRING; 4896.SPAC3H8.08c.1; -.
DR iPTMnet; Q10144; -.
DR MaxQB; Q10144; -.
DR PaxDb; Q10144; -.
DR PRIDE; Q10144; -.
DR EnsemblFungi; SPAC3H8.08c.1; SPAC3H8.08c.1:pep; SPAC3H8.08c.
DR GeneID; 2543636; -.
DR KEGG; spo:SPAC3H8.08c; -.
DR PomBase; SPAC3H8.08c; -.
DR VEuPathDB; FungiDB:SPAC3H8.08c; -.
DR HOGENOM; CLU_037354_0_0_1; -.
DR InParanoid; Q10144; -.
DR OMA; KSCLNCR; -.
DR PRO; PR:Q10144; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; NAS:PomBase.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; NAS:PomBase.
DR CDD; cd00067; GAL4; 1.
DR Gene3D; 4.10.240.10; -; 1.
DR InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR Pfam; PF00172; Zn_clus; 1.
DR SMART; SM00066; GAL4; 1.
DR SUPFAM; SSF57701; SSF57701; 1.
DR PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 4: Predicted;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc.
FT CHAIN 1..563
FT /note="Uncharacterized transcriptional regulatory protein
FT C3H8.08c"
FT /id="PRO_0000115009"
FT DNA_BIND 19..45
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT REGION 56..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 563 AA; 64690 MW; C32CDBEA4F84D358 CRC64;
MSSSPPALKK FRKRSPKSCL ICRRRKVKCD RQQPCSRCKE RNEVCTYADD TIDKMNVGPH
PSHSENASDS ETTLEVSPDI NPKKNEKFDF YGWRSLFELI KYRKDSDMCS SRPSFSIQAY
SSYKDNVVVE SLANLLPPFC ISQKIVNLFF KTLNVVCPIY DQETVEKSLN NIESPESFSY
EDAFTLLPII AATIQLSDLP DVILNFYNSA GITPLESSRL INLKLNEISE QEYKHLCLPD
KEIIQMLLLR AYATKFRTRI RGVNTDLCRS IHVSTLVTPL FQVTEKIGKN TSDLWFALCE
IDGLECVLKY RPPFIQHDTY GRLKPLRCFF NDDISYNFHL LLGRLLDCGV SIYKSVHSLT
VSKFIDKLES YESQLSLILV DIEAKFYDPS NEDIQFRYIF LKMVFWTARV NLYQCFITLD
SGILEDEETI IGNLGESCIQ CVRLLISQIT ILEKRGWLLV ALLEIIHALM LAAFCRDKGF
EVPSDLGDIT LYVQERMVDI VTFDDGMAVR FGYVLRFINS MLHPNEPPMQ DAEPETTEDP
SKLFADIFDF TSNYFIPSAL LDQ