YB0G_SCHPO
ID YB0G_SCHPO Reviewed; 533 AA.
AC P87157;
DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Probable ADP-ribosylation factor-binding protein C25H2.16c;
GN ORFNames=SPBC25H2.16c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-320, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- FUNCTION: May play a role in the regulation of membrane traffic through
CC the trans-Golgi network. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the GGA protein family. {ECO:0000305}.
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DR EMBL; CU329671; CAB08775.1; -; Genomic_DNA.
DR PIR; T40011; T40011.
DR RefSeq; NP_596351.1; NM_001022271.2.
DR AlphaFoldDB; P87157; -.
DR SMR; P87157; -.
DR BioGRID; 277097; 9.
DR STRING; 4896.SPBC25H2.16c.1; -.
DR iPTMnet; P87157; -.
DR MaxQB; P87157; -.
DR PaxDb; P87157; -.
DR PRIDE; P87157; -.
DR EnsemblFungi; SPBC25H2.16c.1; SPBC25H2.16c.1:pep; SPBC25H2.16c.
DR GeneID; 2540570; -.
DR KEGG; spo:SPBC25H2.16c; -.
DR PomBase; SPBC25H2.16c; -.
DR VEuPathDB; FungiDB:SPBC25H2.16c; -.
DR eggNOG; KOG1087; Eukaryota.
DR HOGENOM; CLU_017092_0_0_1; -.
DR InParanoid; P87157; -.
DR OMA; VNDRNPT; -.
DR PhylomeDB; P87157; -.
DR PRO; PR:P87157; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR GO; GO:0032588; C:trans-Golgi network membrane; EXP:PomBase.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IBA:GO_Central.
DR GO; GO:0099638; P:endosome to plasma membrane protein transport; IMP:PomBase.
DR GO; GO:0006895; P:Golgi to endosome transport; IMP:PomBase.
DR GO; GO:0006896; P:Golgi to vacuole transport; IMP:PomBase.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IBA:GO_Central.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR008153; GAE_dom.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR002014; VHS_dom.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; SSF48464; 1.
DR SUPFAM; SSF49348; SSF49348; 1.
DR PROSITE; PS50180; GAE; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 1: Evidence at protein level;
KW Golgi apparatus; Phosphoprotein; Protein transport; Reference proteome;
KW Transport.
FT CHAIN 1..533
FT /note="Probable ADP-ribosylation factor-binding protein
FT C25H2.16c"
FT /id="PRO_0000353801"
FT DOMAIN 15..151
FT /note="VHS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00218"
FT DOMAIN 178..305
FT /note="GAT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00373"
FT DOMAIN 417..532
FT /note="GAE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00093"
FT MOD_RES 320
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 533 AA; 59482 MW; FC6B5144063E6F59 CRC64;
MSSAKRRLYS LIQNATEPYA FEPDLAVNLD IADLINQTGG NLPREAAFAI VRKVNDRNPT
VAYLALNLLD ICVKNCGYAF RLQIASKEFL NELVRRFPER PPSRLNKIQV MILSLIEEWR
KTICRVDRYK EDLGFIRDMH RLLSYKGYTF PEIDKENLAV LSQKSVLKTA EELEKEDREA
MSAKLQELIR RGTPADLAEA NKLMKVMAGY DTEQKQKYKE HVLVDLEKVK RKAALFGEML
NEVSESDKLA SGDLYDELAY SLKAAQRKVD KILEEMSPED DSYVTVSDLK SLIASLLTQY
DHLLEGDFSS ARTVAADNNS LLQATTESAK SNSKTSANAS NTQSAMDLLI DLDIGSDAQS
PSLPASSSQM PTSSFNMESL SQSLLGTVEA PAEVGAISLT ESFNSPVSNS SPNVPINNFT
STCAFENSHL NFQITPKSKT RDQVVLLATY TNLSPYDTVE NLQSFIAVPK KYNLVLQPQS
GTNLSPLQKD GIYQEMIVTK LLDVTELPVR FKLTYKVNGR SQEYTGQSSI RLL
