YB126_YEAST
ID YB126_YEAST Reviewed; 68 AA.
AC Q8TGU7; I2HB53;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Uncharacterized protein YBR126W-A {ECO:0000305};
GN OrderedLocusNames=YBR126W-A {ECO:0000312|SGD:S000028600};
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7813418; DOI=10.1002/j.1460-2075.1994.tb06923.x;
RA Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C.,
RA Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M.,
RA Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M.,
RA Cziepluch C., Demolis N., Delaveau T., Doignon F., Domdey H.,
RA Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D.,
RA Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N.,
RA Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J.,
RA Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C.,
RA Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P.,
RA Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y.,
RA Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F.,
RA Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E.,
RA Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M.,
RA Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B.,
RA Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L.,
RA Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M.,
RA Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S.,
RA Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K.,
RA Mewes H.-W., Kleine K.;
RT "Complete DNA sequence of yeast chromosome II.";
RL EMBO J. 13:5795-5809(1994).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11753363; DOI=10.1038/nbt0102-58;
RA Kumar A., Harrison P.M., Cheung K.-H., Lan N., Echols N., Bertone P.,
RA Miller P., Gerstein M.B., Snyder M.;
RT "An integrated approach for finding overlooked genes in yeast.";
RL Nat. Biotechnol. 20:58-63(2002).
RN [4]
RP IDENTIFICATION.
RX PubMed=22194413; DOI=10.1126/science.1215110;
RA Brar G.A., Yassour M., Friedman N., Regev A., Ingolia N.T., Weissman J.S.;
RT "High-resolution view of the yeast meiotic program revealed by ribosome
RT profiling.";
RL Science 335:552-557(2012).
RN [5]
RP SUBCELLULAR LOCATION.
RX PubMed=26928762; DOI=10.1038/nmeth.3795;
RA Yofe I., Weill U., Meurer M., Chuartzman S., Zalckvar E., Goldman O.,
RA Ben-Dor S., Schuetze C., Wiedemann N., Knop M., Khmelinskii A.,
RA Schuldiner M.;
RT "One library to make them all: streamlining the creation of yeast libraries
RT via a SWAp-Tag strategy.";
RL Nat. Methods 13:371-378(2016).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=29897761; DOI=10.1021/acs.jproteome.8b00032;
RA He C., Jia C., Zhang Y., Xu P.;
RT "Enrichment-based proteogenomics identifies microproteins, missing
RT proteins, and novel smORFs in Saccharomyces cerevisiae.";
RL J. Proteome Res. 17:2335-2344(2018).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000269|PubMed:26928762}. Membrane {ECO:0000255}; Single-pass
CC membrane protein {ECO:0000255}.
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DR EMBL; Z35995; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; Z35996; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AF479888; AAL79201.1; -; Genomic_DNA.
DR EMBL; BK006936; DAA35095.1; -; Genomic_DNA.
DR RefSeq; NP_001257669.1; NM_001270740.1.
DR AlphaFoldDB; Q8TGU7; -.
DR BioGRID; 4312349; 2.
DR IntAct; Q8TGU7; 1.
DR STRING; 4932.YBR126W-A; -.
DR iPTMnet; Q8TGU7; -.
DR MaxQB; Q8TGU7; -.
DR PaxDb; Q8TGU7; -.
DR PRIDE; Q8TGU7; -.
DR EnsemblFungi; YBR126W-A_mRNA; YBR126W-A; YBR126W-A.
DR GeneID; 13393614; -.
DR KEGG; sce:YBR126W-A; -.
DR SGD; S000028600; YBR126W-A.
DR VEuPathDB; FungiDB:YBR126W-A; -.
DR HOGENOM; CLU_2795384_0_0_1; -.
DR BioCyc; YEAST:G3O-29263-MON; -.
DR PRO; PR:Q8TGU7; -.
DR Proteomes; UP000002311; Chromosome II.
DR RNAct; Q8TGU7; protein.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:SGD.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..68
FT /note="Uncharacterized protein YBR126W-A"
FT /id="PRO_0000299747"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 68 AA; 7759 MW; 7DF805E7FC555EFF CRC64;
MAITPDKQKK EQQHQPQNGP LDYAHICKCI AMFFVVAGVV LMFFETGLDP EQKEQIKRLH
QLDGIPHA
