YB33_SCHPO
ID YB33_SCHPO Reviewed; 891 AA.
AC O14338; Q9US77;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Uncharacterized serine-rich protein C2F12.03c;
GN ORFNames=SPBC2F12.03c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 88-288, AND SUBCELLULAR
RP LOCATION.
RC STRAIN=ATCC 38364 / 968;
RX PubMed=10759889; DOI=10.1046/j.1365-2443.2000.00317.x;
RA Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T.,
RA Hiraoka Y.;
RT "Large-scale screening of intracellular protein localization in living
RT fission yeast cells by the use of a GFP-fusion genomic DNA library.";
RL Genes Cells 5:169-190(2000).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-261; SER-263; SER-265 AND
RP SER-268, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10759889}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329671; CAB10152.1; -; Genomic_DNA.
DR EMBL; AB027993; BAA87297.1; -; Genomic_DNA.
DR PIR; T40137; T40137.
DR RefSeq; NP_595712.1; NM_001021609.2.
DR AlphaFoldDB; O14338; -.
DR BioGRID; 276875; 98.
DR STRING; 4896.SPBC2F12.03c.1; -.
DR iPTMnet; O14338; -.
DR MaxQB; O14338; -.
DR PaxDb; O14338; -.
DR PRIDE; O14338; -.
DR EnsemblFungi; SPBC2F12.03c.1; SPBC2F12.03c.1:pep; SPBC2F12.03c.
DR GeneID; 2540346; -.
DR KEGG; spo:SPBC2F12.03c; -.
DR PomBase; SPBC2F12.03c; -.
DR VEuPathDB; FungiDB:SPBC2F12.03c; -.
DR eggNOG; ENOG502R7AH; Eukaryota.
DR HOGENOM; CLU_328770_0_0_1; -.
DR OMA; MSARDSC; -.
DR Reactome; R-SPO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:O14338; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IGI:PomBase.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR018834; DNA/RNA-bd_Est1-type.
DR InterPro; IPR045153; Est1/Ebs1-like.
DR InterPro; IPR019458; Est1_N.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR15696; PTHR15696; 2.
DR Pfam; PF10374; EST1; 1.
DR Pfam; PF10373; EST1_DNA_bind; 1.
DR SUPFAM; SSF48452; SSF48452; 1.
PE 1: Evidence at protein level;
KW Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..891
FT /note="Uncharacterized serine-rich protein C2F12.03c"
FT /id="PRO_0000116497"
FT REGION 48..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..66
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 261
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 263
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 265
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 268
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 891 AA; 98568 MW; 62747D02EB121F6E CRC64;
MSAIDSCEHT VSWKLCEQKY NEATTLLSKL KKLLGNFKEN CTSVVVDGHK KPRSESRKKY
DAKKQHQSSH FATPVKGVES SEPTEKKKRN KEALWLRARQ KKWKEIFELC QKITSLLGGT
ILIDVSFSME KDVLTYLWMR VHYQVISFFK HRIYEASTQH DPELLSSLVT MHIQYLNSTI
QFYTTLIAII GELYHLQCLS PLTSFFTSCV TPKTILESPL RKQGSHNWKT STNSQSRLAA
LFSSIFEDSC LEVDSVKRLL SGSPSSSSSP LKKDSSSNSL TYEPALTDHK PQYLVLCVYR
SLIYIGDVHR YLAEVRSPNV PDYQVSRRYY VMAANVAPDY GVHFHQLGLI EVADARSSSR
KSSSGQSSSL KGNVNVEDKR LIQALPAISF FFLSSISPNN VAASSAKTSL FIALKRCFGK
TNDGSNPCLY HKESSAISLF LRLYAIAFSN TDADYIQDSG PLFKRVRFLL SESLKSGLFS
ESSLLQMTYC ALAARVLAPF IGFSDSGEHG ESYPNLKLAT QTTTMFFEVL SDSVNSQLPL
QALTSGVSSK KDGNFDDLVE RRQYGSLSSN AVLMPMLLPL CVLTSSCLQN GDVWLTKDIR
TGLSQIFNRL SFFLENTNQT APDDSVLVRC SSKSIGLLFF FPLVKVCGVP RDTLQWLYFS
NHYPFNEEGK GPQVDDSDAL ITIALDSLYV LLNMRAKSTP NSTSFSSPPT PHRSPFSGQA
FTGMGLSNYS LMSSSSFPSA QSSPTSPFLS GTPSIANQSS SIASLQFGRM VDSLVGPVQP
IPAQTTGCSV HSLQQRTFSN ESPRAVDSGF SRTSTPFSES TSSYPLVSGN LSSCETHLNG
SPQNGHLQGE RVLFRPLRSP ALNTFSTPAT EPPEHLVLSE LLKKMVNISN N
