YB92_SCHPO
ID YB92_SCHPO Reviewed; 603 AA.
AC O42967;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Uncharacterized ubiquitin-like protein C1E8.02;
GN ORFNames=SPBC1E8.02;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-566, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:16823372}; Single-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAA16835.1; -; Genomic_DNA.
DR PIR; T39866; T39866.
DR RefSeq; NP_595800.1; NM_001021702.2.
DR AlphaFoldDB; O42967; -.
DR SMR; O42967; -.
DR BioGRID; 277182; 7.
DR STRING; 4896.SPBC1E8.02.1; -.
DR iPTMnet; O42967; -.
DR MaxQB; O42967; -.
DR PaxDb; O42967; -.
DR PRIDE; O42967; -.
DR EnsemblFungi; SPBC1E8.02.1; SPBC1E8.02.1:pep; SPBC1E8.02.
DR PomBase; SPBC1E8.02; -.
DR VEuPathDB; FungiDB:SPBC1E8.02; -.
DR eggNOG; KOG0010; Eukaryota.
DR HOGENOM; CLU_452809_0_0_1; -.
DR InParanoid; O42967; -.
DR OMA; ECAYLLS; -.
DR Reactome; R-SPO-8856825; Cargo recognition for clathrin-mediated endocytosis.
DR PRO; PR:O42967; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031593; F:polyubiquitin modification-dependent protein binding; IBA:GO_Central.
DR GO; GO:0032446; P:protein modification by small protein conjugation; ISM:PomBase.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR Pfam; PF00240; ubiquitin; 1.
DR SMART; SM00213; UBQ; 1.
DR SUPFAM; SSF54236; SSF54236; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 1: Evidence at protein level;
KW Endoplasmic reticulum; Membrane; Phosphoprotein; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..603
FT /note="Uncharacterized ubiquitin-like protein C1E8.02"
FT /id="PRO_0000310777"
FT TRANSMEM 496..516
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 4..79
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00214"
FT REGION 85..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..117
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..578
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 566
FT /note="Phosphothreonine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 603 AA; 66567 MW; D41BAF595AC500BF CRC64;
MSEYRIRVTT VDQKVGIFQV PRTKTVLELK ELIAVTFEAP ADRLKLIHAG RVLRNETPLE
EILHDATDLV TFHLVIAVFN STSTTLPSAT SSSVPQSRTS ELSSTNSIPT PRITSLNPEE
LSRRERAQRL LQTYNSFHGS GLGGLFPNIH RELESHGFSL PTHEQSSPVA ESLDNSVSSA
LSPHLETLRR RNLSIHHQHI QAHEMAQESL ETRNPGNISS SSAPLASDQS PTVSSNHIHA
SGNLALGSNS GLNPRSPNSF SSPLDNPALH TVDSTNVNGS LSPLSNSSSI NQVHQNETHG
STISVPNPNL SQMGPSHSSS VPSNLSPNPA QNENPSTTSI PSINNQPFPS GLSASNSNFA
SSSFIPQSVP QLLPIYYQTI FYNGNYYLQQ LPSASPPTMF RDHSFAPLVS PSIVSPYGVL
ENEETGECAF LFSPNASQPH FQPRAPTFGI PRNVRSLFTL PFFHTIRNIE RHFRLFIRLA
LFCVLTTYNV SLSQTILLTS IMSVVFLLQT GALAPFINDN PLIQSGMRHI RNLQDEYRRR
RNRTAQRVVE IPNETQTEDE QDGTNTPDNR ADAEERELTR SQRIYRTVVR TIVAFALSFV
PRA
