YBA9_SCHPO
ID YBA9_SCHPO Reviewed; 186 AA.
AC O42901; P79056;
DT 01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 3.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Uncharacterized protein C119.09c;
GN ORFNames=SPBC119.09c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 37-186.
RC STRAIN=PR745;
RX PubMed=9501991; DOI=10.1093/dnares/4.6.363;
RA Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.;
RT "Identification of open reading frames in Schizosaccharomyces pombe
RT cDNAs.";
RL DNA Res. 4:363-369(1997).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC Multi-pass membrane protein {ECO:0000305}.
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DR EMBL; CU329671; CAA17924.1; -; Genomic_DNA.
DR EMBL; AB001024; BAA19218.1; -; mRNA.
DR PIR; T39307; T39307.
DR RefSeq; NP_595290.1; NM_001021197.2.
DR AlphaFoldDB; O42901; -.
DR SMR; O42901; -.
DR BioGRID; 276592; 4.
DR IntAct; O42901; 1.
DR STRING; 4896.SPBC119.09c.1; -.
DR iPTMnet; O42901; -.
DR SwissPalm; O42901; -.
DR MaxQB; O42901; -.
DR PaxDb; O42901; -.
DR PRIDE; O42901; -.
DR EnsemblFungi; SPBC119.09c.1; SPBC119.09c.1:pep; SPBC119.09c.
DR GeneID; 2540054; -.
DR KEGG; spo:SPBC119.09c; -.
DR PomBase; SPBC119.09c; -.
DR VEuPathDB; FungiDB:SPBC119.09c; -.
DR eggNOG; KOG3319; Eukaryota.
DR HOGENOM; CLU_072117_2_0_1; -.
DR InParanoid; O42901; -.
DR OMA; STHYTHF; -.
DR PhylomeDB; O42901; -.
DR Reactome; R-SPO-6798695; Neutrophil degranulation.
DR PRO; PR:O42901; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IC:PomBase.
DR GO; GO:0035339; C:SPOTS complex; IBA:GO_Central.
DR GO; GO:0034620; P:cellular response to unfolded protein; ISO:PomBase.
DR GO; GO:0090156; P:cellular sphingolipid homeostasis; IBA:GO_Central.
DR GO; GO:0006672; P:ceramide metabolic process; IBA:GO_Central.
DR GO; GO:1900060; P:negative regulation of ceramide biosynthetic process; IBA:GO_Central.
DR InterPro; IPR007203; ORMDL.
DR PANTHER; PTHR12665; PTHR12665; 1.
DR Pfam; PF04061; ORMDL; 1.
DR PIRSF; PIRSF018147; ORMDL; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..186
FT /note="Uncharacterized protein C119.09c"
FT /id="PRO_0000116508"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 41
FT /note="Y -> H (in Ref. 2; BAA19218)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 186 AA; 21467 MW; 13520888EC2389F0 CRC64;
MGSSSSRRRS SSLVTKVPKP TIDDRLDQGS ATNYNSNWVN YKGAWVIHIV LIAALRLIFH
AIPSVSRELA WTLTNLTYMA GSFIMFHWVT GTPFEFNGGA YDRLTMWEQL DEGNQYTPAR
KYLLVLPIIL FLMSTHYTHY NGWMFLVNIW ALFMVLIPKL PAVHRKRIFG IQKLSLRDDD
NDSIPR