YBAB_ECOLI
ID YBAB_ECOLI Reviewed; 109 AA.
AC P0A8B5; P09994; P17577; Q2MBV6;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Nucleoid-associated protein YbaB {ECO:0000255|HAMAP-Rule:MF_00274};
GN Name=ybaB {ECO:0000255|HAMAP-Rule:MF_00274};
GN OrderedLocusNames=b0471, JW0460;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=2674903; DOI=10.1093/nar/17.17.6781;
RA Mahdi A.A., Lloyd R.G.;
RT "The recR locus of Escherichia coli K-12: molecular cloning, DNA sequencing
RT and identification of the gene product.";
RL Nucleic Acids Res. 17:6781-6794(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=1698765; DOI=10.1128/jb.172.10.6042-6047.1990;
RA Yeung T., Mullin D.A., Chen K.S., Craig E.A., Bardwell J.C.A., Walker J.R.;
RT "Sequence and expression of the Escherichia coli recR locus.";
RL J. Bacteriol. 172:6042-6047(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-75.
RX PubMed=3534795; DOI=10.1093/nar/14.20.8091;
RA Flower A.M., McHenry C.S.;
RT "The adjacent dnaZ and dnaX genes of Escherichia coli are contained within
RT one continuous open reading frame.";
RL Nucleic Acids Res. 14:8091-8101(1986).
RN [6]
RP DNA-BINDING, AND SUBUNIT.
RX PubMed=19594923; DOI=10.1186/1471-2180-9-137;
RA Cooley A.E., Riley S.P., Kral K., Miller M.C., DeMoll E., Fried M.G.,
RA Stevenson B.;
RT "DNA-binding by Haemophilus influenzae and Escherichia coli YbaB, members
RT of a widely-distributed bacterial protein family.";
RL BMC Microbiol. 9:137-137(2009).
RN [7]
RP X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS), AND SUBUNIT.
RG New York structural genomics research consortium (NYSGRC);
RT "Structure of E. coli Ybab.";
RL Submitted (JAN-2005) to the PDB data bank.
CC -!- FUNCTION: Binds to DNA and alters its conformation. May be involved in
CC regulation of gene expression, nucleoid organization and DNA
CC protection. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00274,
CC ECO:0000269|PubMed:19594923, ECO:0000269|Ref.7}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC Rule:MF_00274}.
CC -!- SIMILARITY: Belongs to the YbaB/EbfC family. {ECO:0000255|HAMAP-
CC Rule:MF_00274}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; M38777; AAA23458.1; -; Genomic_DNA.
DR EMBL; X15761; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; U00096; AAC73573.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76250.1; -; Genomic_DNA.
DR EMBL; X04487; CAA28176.1; -; Genomic_DNA.
DR PIR; A30371; QQECZG.
DR RefSeq; NP_415004.1; NC_000913.3.
DR RefSeq; WP_000467098.1; NZ_STEB01000007.1.
DR PDB; 1PUG; X-ray; 2.20 A; A/B/C/D=1-109.
DR PDBsum; 1PUG; -.
DR AlphaFoldDB; P0A8B5; -.
DR SMR; P0A8B5; -.
DR BioGRID; 4261967; 59.
DR DIP; DIP-48059N; -.
DR IntAct; P0A8B5; 12.
DR STRING; 511145.b0471; -.
DR jPOST; P0A8B5; -.
DR PaxDb; P0A8B5; -.
DR PRIDE; P0A8B5; -.
DR EnsemblBacteria; AAC73573; AAC73573; b0471.
DR EnsemblBacteria; BAE76250; BAE76250; BAE76250.
DR GeneID; 66754946; -.
DR GeneID; 945104; -.
DR KEGG; ecj:JW0460; -.
DR KEGG; eco:b0471; -.
DR PATRIC; fig|511145.12.peg.491; -.
DR EchoBASE; EB1092; -.
DR eggNOG; COG0718; Bacteria.
DR HOGENOM; CLU_140930_0_0_6; -.
DR InParanoid; P0A8B5; -.
DR OMA; MGNMMKQ; -.
DR PhylomeDB; P0A8B5; -.
DR BioCyc; EcoCyc:EG11100-MON; -.
DR EvolutionaryTrace; P0A8B5; -.
DR PRO; PR:P0A8B5; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0043590; C:bacterial nucleoid; IEA:UniProtKB-UniRule.
DR GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR GO; GO:0003677; F:DNA binding; IDA:EcoCyc.
DR GO; GO:0009314; P:response to radiation; IMP:EcoCyc.
DR Gene3D; 3.30.1310.10; -; 1.
DR HAMAP; MF_00274; DNA_YbaB_EbfC; 1.
DR InterPro; IPR036894; YbaB-like_sf.
DR InterPro; IPR004401; YbaB/EbfC.
DR PANTHER; PTHR33449; PTHR33449; 1.
DR Pfam; PF02575; YbaB_DNA_bd; 1.
DR PIRSF; PIRSF004555; UCP004555; 1.
DR SUPFAM; SSF82607; SSF82607; 1.
DR TIGRFAMs; TIGR00103; DNA_YbaB_EbfC; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; DNA-binding; Reference proteome.
FT CHAIN 1..109
FT /note="Nucleoid-associated protein YbaB"
FT /id="PRO_0000170391"
FT STRAND 13..15
FT /evidence="ECO:0007829|PDB:1PUG"
FT HELIX 18..29
FT /evidence="ECO:0007829|PDB:1PUG"
FT STRAND 32..37
FT /evidence="ECO:0007829|PDB:1PUG"
FT HELIX 38..40
FT /evidence="ECO:0007829|PDB:1PUG"
FT STRAND 42..47
FT /evidence="ECO:0007829|PDB:1PUG"
FT STRAND 52..57
FT /evidence="ECO:0007829|PDB:1PUG"
FT HELIX 59..61
FT /evidence="ECO:0007829|PDB:1PUG"
FT HELIX 66..97
FT /evidence="ECO:0007829|PDB:1PUG"
SQ SEQUENCE 109 AA; 12015 MW; 5E05A853ABDCFABF CRC64;
MFGKGGLGNL MKQAQQMQEK MQKMQEEIAQ LEVTGESGAG LVKVTINGAH NCRRVEIDPS
LLEDDKEMLE DLVAAAFNDA ARRIEETQKE KMASVSSGMQ LPPGFKMPF
