YBAT_ECOLI
ID YBAT_ECOLI Reviewed; 430 AA.
AC P77400; Q2MBU1;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 150.
DE RecName: Full=Inner membrane transport protein YbaT;
GN Name=ybaT; OrderedLocusNames=b0486, JW0475;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- FUNCTION: Probable amino-acid or metabolite transport protein.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. {ECO:0000305}.
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DR EMBL; U82664; AAB40240.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73588.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76265.1; -; Genomic_DNA.
DR PIR; E64779; E64779.
DR RefSeq; NP_415019.1; NC_000913.3.
DR RefSeq; WP_000982172.1; NZ_STEB01000007.1.
DR AlphaFoldDB; P77400; -.
DR SMR; P77400; -.
DR BioGRID; 4261285; 128.
DR DIP; DIP-11308N; -.
DR IntAct; P77400; 1.
DR STRING; 511145.b0486; -.
DR TCDB; 2.A.3.6.4; the amino acid-polyamine-organocation (apc) family.
DR jPOST; P77400; -.
DR PaxDb; P77400; -.
DR PRIDE; P77400; -.
DR EnsemblBacteria; AAC73588; AAC73588; b0486.
DR EnsemblBacteria; BAE76265; BAE76265; BAE76265.
DR GeneID; 66671212; -.
DR GeneID; 945363; -.
DR KEGG; ecj:JW0475; -.
DR KEGG; eco:b0486; -.
DR PATRIC; fig|1411691.4.peg.1790; -.
DR EchoBASE; EB3037; -.
DR eggNOG; COG0531; Bacteria.
DR HOGENOM; CLU_007946_15_2_6; -.
DR InParanoid; P77400; -.
DR OMA; KPFWPSC; -.
DR PhylomeDB; P77400; -.
DR BioCyc; EcoCyc:B0486-MON; -.
DR PRO; PR:P77400; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0009268; P:response to pH; IEP:EcoCyc.
DR GO; GO:1990169; P:stress response to copper ion; IDA:EcoCyc.
DR InterPro; IPR002293; AA/rel_permease1.
DR Pfam; PF13520; AA_permease_2; 1.
PE 1: Evidence at protein level;
KW Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..430
FT /note="Inner membrane transport protein YbaT"
FT /id="PRO_0000054214"
FT TOPO_DOM 1..14
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 36..38
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 60..88
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 89..109
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 110..128
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 150..157
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 179..192
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 214..228
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 250..272
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 294..325
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 326..346
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 347
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 348..368
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 369..379
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 401..403
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 404..424
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 425..430
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 430 AA; 45659 MW; 7D6ACD50AD253FE9 CRC64;
MMNTEGNNGN KPLGLWNVVS IGIGAMVGAG IFALLGQAAL LMEASTWVAF AFGGIVAMFS
GYAYARLGAS YPSNGGIIDF FRRGLGNGVF SLALSLLYLL TLAVSIAMVA RAFGAYAVQF
LHEGSQEEHL ILLYALGIIA VMTLFNSLSN HAVGRLEVIL VGIKMMILLL LIIAGVWSLQ
PAHISVSAPP SSGAFFSCIG ITFLAYAGFG MMANAADKVK DPQVIMPRAF LVAIGVTTLL
YISLALVLLS DVSALELEKY ADTAVAQAAS PLLGHVGYVI VVIGALLATA SAINANLFAV
FNIMDNMGSE RELPKLMNKS LWRQSTWGNI IVVVLIMLMT AALNLGSLAS VASATFLICY
LAVFVVAIRL RHDIHASLPI LIVGTLVMLL VIVGFIYSLW SQGSRALIWI IGSLLLSLIV
AMVMKRNKTV
