ID   YBBO_ECOL6              Reviewed;         269 AA.
AC   P0AFP5; P77388;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Uncharacterized oxidoreductase YbbO;
DE            EC=1.-.-.-;
GN   Name=ybbO; OrderedLocusNames=c0614;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; AE014075; AAN79091.1; -; Genomic_DNA.
DR   RefSeq; WP_000148959.1; NC_004431.1.
DR   AlphaFoldDB; P0AFP5; -.
DR   SMR; P0AFP5; -.
DR   STRING; 199310.c0614; -.
DR   PRIDE; P0AFP5; -.
DR   EnsemblBacteria; AAN79091; AAN79091; c0614.
DR   GeneID; 60903777; -.
DR   KEGG; ecc:c0614; -.
DR   eggNOG; COG0300; Bacteria.
DR   HOGENOM; CLU_010194_2_9_6; -.
DR   OMA; QMDVTDR; -.
DR   BioCyc; ECOL199310:C0614-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..269
FT                   /note="Uncharacterized oxidoreductase YbbO"
FT                   /id="PRO_0000054823"
FT   ACT_SITE        159
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         15..41
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         146
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   269 AA;  29410 MW;  3EFC0E423AE89D87 CRC64;
     MTHKATEILT GKVMQKSVLI TGCSSGIGLE SALELKRQGF HVLAGCRKPD DVERMNSMGF
     TGVLIDLDSP ESVDRAADEV IALTDNCLYG IFNNAGFGMY GPLSTISRAQ MEQQFSANFF
     GAHQLTMRLL PAMLPHGEGR IVMTSSVMGL ISTPGRGAYA ASKYALEAWS DALRMELRHS
     GIKVSLIEPG PIRTRFTDNV NQTQSDKPVE NPGIAARFTL GPEAVVDKVR HAFISEKPKM
     RYPVTLVTWA VMVLKRLLPG RVMDKILQG