YBCL_ECOLI
ID YBCL_ECOLI Reviewed; 183 AA.
AC P77368; Q2MBN6;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 149.
DE RecName: Full=UPF0098 protein YbcL;
DE Flags: Precursor;
GN Name=ybcL; OrderedLocusNames=b0545, JW0533;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP X-RAY CRYSTALLOGRAPHY (1.81 ANGSTROMS), SUBUNIT, AND SUBCELLULAR LOCATION.
RX PubMed=11439028; DOI=10.1006/jmbi.2001.4784;
RA Serre L., Pereira de Jesus K., Zelwer C., Bureaud N., Schoentgen F.,
RA Benedetti H.;
RT "Crystal structures of YBHB and YBCL from Escherichia coli, two bacterial
RT homologues to a Raf kinase inhibitor protein.";
RL J. Mol. Biol. 310:617-634(2001).
CC -!- SUBUNIT: Homodimer. {ECO:0000269|PubMed:11439028}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000269|PubMed:11439028}.
CC -!- MISCELLANEOUS: Encoded by the cryptic lambdoid prophage DLP12.
CC -!- SIMILARITY: Belongs to the UPF0098 family. {ECO:0000305}.
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DR EMBL; U82598; AAB40742.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73646.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76320.1; -; Genomic_DNA.
DR PIR; G64786; G64786.
DR RefSeq; NP_415077.1; NC_000913.3.
DR RefSeq; WP_001306955.1; NZ_LN832404.1.
DR PDB; 1FUX; X-ray; 1.81 A; A/B=22-183.
DR PDBsum; 1FUX; -.
DR AlphaFoldDB; P77368; -.
DR SMR; P77368; -.
DR BioGRID; 4262074; 22.
DR STRING; 511145.b0545; -.
DR jPOST; P77368; -.
DR PaxDb; P77368; -.
DR PRIDE; P77368; -.
DR EnsemblBacteria; AAC73646; AAC73646; b0545.
DR EnsemblBacteria; BAE76320; BAE76320; BAE76320.
DR GeneID; 945165; -.
DR KEGG; ecj:JW0533; -.
DR KEGG; eco:b0545; -.
DR PATRIC; fig|1411691.4.peg.1732; -.
DR EchoBASE; EB3393; -.
DR eggNOG; COG1881; Bacteria.
DR HOGENOM; CLU_083918_2_0_6; -.
DR InParanoid; P77368; -.
DR OMA; LRWEGFP; -.
DR PhylomeDB; P77368; -.
DR BioCyc; EcoCyc:G6301-MON; -.
DR EvolutionaryTrace; P77368; -.
DR PRO; PR:P77368; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoCyc.
DR GO; GO:0043086; P:negative regulation of catalytic activity; IEA:GOC.
DR CDD; cd00865; PEBP_bact_arch; 1.
DR Gene3D; 3.90.280.10; -; 1.
DR InterPro; IPR008914; PEBP.
DR InterPro; IPR036610; PEBP-like_sf.
DR InterPro; IPR005247; YbhB_YbcL.
DR PANTHER; PTHR30289; PTHR30289; 1.
DR Pfam; PF01161; PBP; 1.
DR SUPFAM; SSF49777; SSF49777; 1.
DR TIGRFAMs; TIGR00481; TIGR00481; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Disulfide bond; Periplasm; Reference proteome; Signal.
FT SIGNAL 1..21
FT CHAIN 22..183
FT /note="UPF0098 protein YbcL"
FT /id="PRO_0000036212"
FT DISULFID 46..129
FT STRAND 23..25
FT /evidence="ECO:0007829|PDB:1FUX"
FT HELIX 37..39
FT /evidence="ECO:0007829|PDB:1FUX"
FT STRAND 55..58
FT /evidence="ECO:0007829|PDB:1FUX"
FT STRAND 66..73
FT /evidence="ECO:0007829|PDB:1FUX"
FT STRAND 82..91
FT /evidence="ECO:0007829|PDB:1FUX"
FT TURN 99..102
FT /evidence="ECO:0007829|PDB:1FUX"
FT STRAND 121..124
FT /evidence="ECO:0007829|PDB:1FUX"
FT STRAND 140..147
FT /evidence="ECO:0007829|PDB:1FUX"
FT HELIX 159..167
FT /evidence="ECO:0007829|PDB:1FUX"
FT STRAND 170..176
FT /evidence="ECO:0007829|PDB:1FUX"
SQ SEQUENCE 183 AA; 19476 MW; FF60F20C9CF061A1 CRC64;
MKTLIVSTVL AFITFSAQAA AFQVTSNEIK TGEQLTTSHV FSGFGCEGGN TSPSLTWSGV
PEGTKSFAVT VYDPDAPTGS GWWHWTVVNI PATVTYLPVD AGRRDGTKLP TGAVQGRNDF
GYAGFGGACP PKGDKPHHYQ FKVWALKTEK IPVDSNSSGA LVGYMLNANK IATAEITPVY
EIK
