ID   YBD4_ENCCU              Reviewed;         582 AA.
AC   Q8SQU5;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=ABC transporter-like protein ECU11_1340;
GN   OrderedLocusNames=ECU11_1340;
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1;
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], AND
RP   DEVELOPMENTAL STAGE.
RX   PubMed=16691553; DOI=10.1002/pmic.200500796;
RA   Brosson D., Kuhn L., Delbac F., Garin J., Vivares C.P., Texier C.;
RT   "Proteomic analysis of the eukaryotic parasite Encephalitozoon cuniculi
RT   (microsporidia): a reference map for proteins expressed in late sporogonial
RT   stages.";
RL   Proteomics 6:3625-3635(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in late sporogonial stages.
CC       {ECO:0000269|PubMed:16691553}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; AL590450; CAD26044.1; -; Genomic_DNA.
DR   RefSeq; NP_586440.1; NM_001042273.1.
DR   AlphaFoldDB; Q8SQU5; -.
DR   SMR; Q8SQU5; -.
DR   TCDB; 3.A.1.204.14; the atp-binding cassette (abc) superfamily.
DR   GeneID; 860094; -.
DR   KEGG; ecu:ECU11_1340; -.
DR   VEuPathDB; MicrosporidiaDB:ECU11_1340; -.
DR   HOGENOM; CLU_020421_0_0_1; -.
DR   InParanoid; Q8SQU5; -.
DR   OMA; NTIAVWI; -.
DR   OrthoDB; 131191at2759; -.
DR   Proteomes; UP000000819; Chromosome XI.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..582
FT                   /note="ABC transporter-like protein ECU11_1340"
FT                   /id="PRO_0000383107"
FT   TRANSMEM        335..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        359..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        412..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        436..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        482..502
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        551..571
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          15..257
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          ?316..?519
FT                   /note="ABC transmembrane type-2"
FT   BINDING         47..54
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   582 AA;  65503 MW;  169AC44733E30320 CRC64;
     MKQHTLQLEG VTLDVPNQNL SSNEKYARLI NGLTADFKSG NVYAFMGTSG SGKTTTLETI
     AGLVPSGSRT GGRILVDGQE RNPDEFPYEF AYGDQLGYII DELTVEEFVY YYVVSSLPEE
     SKERVREKMD EVLENLLNIG HIRHNKMKNI SGGEQKRANL ARTFTKMLLL EGELKVVLLD
     EPTSELDAGL ALKLGEFLRD YARRSNSIVL VTVHQPGAEL YNTFDNLLFM NNGEKLYLGP
     SRDFIKFLGT KGIHNDGGPE TNMEFLFSLF TKGSKMSKKY EKQLEQIAKE MNEEKKEEKK
     LRTSDDTEIN FIPNLYVSFQ MAIRQIIIDW RNREILYSLA MPIAMALFLV TGKYIYKDFS
     IATIKASMLS LSLYYVMNPS GLMNDKHYVT EESNRKLYGA AEVWFSSLIS DTLVSILKYC
     IFFGIIYAFG LISMDHAFLG QVLMYTLGGT VSSMLFRSMA SPLSTLGKVF NTTMVLMFQL
     SGALLGAGAL LGALTLWISV IPEGSIPQEE IDAFISNFFD STGSTGSTSI FSKVGSWVIR
     FICLVPKVVR SFLRILFLMF HPFAFFHSSI LDAEKSSYKL FF