YBDR_ECOLI
ID YBDR_ECOLI Reviewed; 412 AA.
AC P77316;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 146.
DE RecName: Full=Uncharacterized zinc-type alcohol dehydrogenase-like protein YbdR;
DE EC=1.-.-.-;
GN Name=ybdR; OrderedLocusNames=b0608, JW0601;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000250};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. Class-III subfamily. {ECO:0000305}.
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DR EMBL; U82598; AAB40809.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73709.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35238.1; -; Genomic_DNA.
DR PIR; F64794; F64794.
DR RefSeq; NP_415141.1; NC_000913.3.
DR RefSeq; WP_000646173.1; NZ_SSZK01000032.1.
DR AlphaFoldDB; P77316; -.
DR SMR; P77316; -.
DR BioGRID; 4259897; 8.
DR DIP; DIP-11355N; -.
DR IntAct; P77316; 6.
DR STRING; 511145.b0608; -.
DR jPOST; P77316; -.
DR PaxDb; P77316; -.
DR PRIDE; P77316; -.
DR EnsemblBacteria; AAC73709; AAC73709; b0608.
DR EnsemblBacteria; BAA35238; BAA35238; BAA35238.
DR GeneID; 949067; -.
DR KEGG; ecj:JW0601; -.
DR KEGG; eco:b0608; -.
DR PATRIC; fig|1411691.4.peg.1660; -.
DR EchoBASE; EB3307; -.
DR eggNOG; COG1063; Bacteria.
DR HOGENOM; CLU_026673_11_3_6; -.
DR InParanoid; P77316; -.
DR OMA; CCRNFGT; -.
DR PhylomeDB; P77316; -.
DR BioCyc; EcoCyc:G6335-MON; -.
DR PRO; PR:P77316; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH_N.
DR InterPro; IPR027399; ADH_N_assoc.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13823; ADH_N_assoc; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; SSF50129; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding; Oxidoreductase; Reference proteome; Zinc.
FT CHAIN 1..412
FT /note="Uncharacterized zinc-type alcohol dehydrogenase-like
FT protein YbdR"
FT /id="PRO_0000160889"
FT BINDING 38
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
FT BINDING 60
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000250"
FT BINDING 90
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 93
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 96
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 104
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
SQ SEQUENCE 412 AA; 44176 MW; 966BB43A8FAB178D CRC64;
MKALTYHGPH HVQVENVPDP GVEQADDIIL RITATAICGS DLHLYRGKIP QVKHGDIFGH
EFMGEVVETG KDVKNLQKGD RVVIPFVIAC GDCFFCRLQQ YAACENTNAG KGAALNKKQI
PAPAALFGYS HLYGGVPGGQ AEYVRVPKGN VGPFKVPPLL SDDKALFLSD ILPTAWQAAK
NAQIQQGSSV AVYGAGPVGL LTIACARLLG AEQIFVVDHH PYRLHFAADR YGAIPINFDE
DSDPAQSIIE QTAGHRGVDA VIDAVGFEAK GSTTETVLTN LKLEGSSGKA LRQCIAAVRR
GGIVSVPGVY AGFIHGFLFG DAFDKGLSFK MGQTHVHAWL GELLPLIEKG LLKPEEIVTH
YMPFEEAARG YEIFEKREEE CRKVILVPGA QSAEAAQKAV SGLVNAMPGG TI
