YBE8_SCHPO
ID YBE8_SCHPO Reviewed; 435 AA.
AC O74763;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 143.
DE RecName: Full=Uncharacterized WD repeat-containing protein C17D11.08;
GN ORFNames=SPBC17D11.08;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-266 AND SER-388, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Golgi
CC apparatus {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAA21079.1; -; Genomic_DNA.
DR PIR; T39719; T39719.
DR RefSeq; NP_596382.1; NM_001022303.2.
DR AlphaFoldDB; O74763; -.
DR SMR; O74763; -.
DR BioGRID; 276172; 19.
DR STRING; 4896.SPBC17D11.08.1; -.
DR iPTMnet; O74763; -.
DR MaxQB; O74763; -.
DR PaxDb; O74763; -.
DR PRIDE; O74763; -.
DR EnsemblFungi; SPBC17D11.08.1; SPBC17D11.08.1:pep; SPBC17D11.08.
DR GeneID; 2539614; -.
DR KEGG; spo:SPBC17D11.08; -.
DR PomBase; SPBC17D11.08; -.
DR VEuPathDB; FungiDB:SPBC17D11.08; -.
DR eggNOG; KOG0290; Eukaryota.
DR HOGENOM; CLU_013694_1_1_1; -.
DR InParanoid; O74763; -.
DR OMA; NEDWMAI; -.
DR PhylomeDB; O74763; -.
DR Reactome; R-SPO-8951664; Neddylation.
DR PRO; PR:O74763; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0080008; C:Cul4-RING E3 ubiquitin ligase complex; ISS:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; ISS:PomBase.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR045159; DCAF7-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19919; PTHR19919; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 1: Evidence at protein level;
KW Cytoplasm; Golgi apparatus; Phosphoprotein; Reference proteome; Repeat;
KW WD repeat.
FT CHAIN 1..435
FT /note="Uncharacterized WD repeat-containing protein
FT C17D11.08"
FT /id="PRO_0000316548"
FT REPEAT 105..149
FT /note="WD 1"
FT REPEAT 164..204
FT /note="WD 2"
FT REPEAT 207..247
FT /note="WD 3"
FT REPEAT 313..353
FT /note="WD 4"
FT REGION 352..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 266
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 388
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 435 AA; 47743 MW; EC48C5ACEA9DA6D2 CRC64;
MTDLRRNRYS ISAGVGKSVL DSLGKFYGSP KRQLPNKFEA GKEYTGYNAP WIPFALDWLK
QGKYSSEWIA MGSLNEEPNN MIQLLKLITG DDGNSHLEKA QAATDLEYPV TKLLWNPSSV
GSNTDSQLLA STDQQLRLWK TDFEAGIDSP LLCQASLSTH VKTHNNAPLT SFDWCKTDPS
YIVVSSLDTT CTVWDIVAQQ SKTQLIAHDK EVYDVAFLKD SINVFVSVGA DGSVRMFDLR
SLDHSTIIYE GDSTFWKRNG DYTNASPPVS APLLRLSACD SDVNLMATFH HNSSDVQMID
IRVPGTAYAT LRGHKGDVNA VKWMPGSKSK LATCGDDCVV SLWDLDQPVN PSPAPTLSVS
GTTPGMTGST SEYVTPVSSV NSMRETASPL NADNQYSPLL SWKLEHEVNN LSWSVKNDGL
AVVYGKSLEI LKVPQ
