YBEC_BACSU
ID YBEC_BACSU Reviewed; 539 AA.
AC Q45577; Q7DL53;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 3.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Probable amino acid-proton symporter YbeC;
GN Name=ybeC; OrderedLocusNames=BSU02120;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RA Haga K., Liu H., Yasumoto K., Takahashi H., Yoshikawa H.;
RT "Sequence analysis of the 70kb region between 17 and 23 degree of the
RT Bacillus subtilis chromosome.";
RL Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP SEQUENCE REVISION TO 319.
RX PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT 168 reference genome a decade later.";
RL Microbiology 155:1758-1775(2009).
RN [4]
RP IDENTIFICATION.
RC STRAIN=168;
RX PubMed=12730183; DOI=10.1128/jb.185.10.3218-3222.2003;
RA Lorca G., Winnen B., Saier M.H. Jr.;
RT "Identification of the L-aspartate transporter in Bacillus subtilis.";
RL J. Bacteriol. 185:3218-3222(2003).
CC -!- FUNCTION: Uptake of an yet unknown amino-acid with the concomitant
CC import of a proton. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. AGT (TC 2.A.3.11) family. {ECO:0000305}.
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DR EMBL; AB006424; BAA33109.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB12006.2; -; Genomic_DNA.
DR PIR; D69748; D69748.
DR RefSeq; NP_388094.2; NC_000964.3.
DR RefSeq; WP_003246447.1; NZ_JNCM01000030.1.
DR AlphaFoldDB; Q45577; -.
DR SMR; Q45577; -.
DR STRING; 224308.BSU02120; -.
DR jPOST; Q45577; -.
DR PaxDb; Q45577; -.
DR PRIDE; Q45577; -.
DR EnsemblBacteria; CAB12006; CAB12006; BSU_02120.
DR GeneID; 938442; -.
DR KEGG; bsu:BSU02120; -.
DR PATRIC; fig|224308.179.peg.218; -.
DR eggNOG; COG0531; Bacteria.
DR InParanoid; Q45577; -.
DR OMA; LGNVQYF; -.
DR PhylomeDB; Q45577; -.
DR BioCyc; BSUB:BSU02120-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR InterPro; IPR002293; AA/rel_permease1.
DR Pfam; PF13520; AA_permease_2; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell membrane; Membrane; Reference proteome; Symport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..539
FT /note="Probable amino acid-proton symporter YbeC"
FT /id="PRO_0000360432"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 238..258
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 283..303
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 346..365
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 369..389
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 401..421
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 424..444
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 457..477
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 486..506
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 319
FT /note="I -> V (in Ref. 1; BAA33109)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 539 AA; 59212 MW; 76209D9A7996BE35 CRC64;
MNQLHRRMGT FSLMMVGLGS MIGSGWLFGA WRAAQIAGPA AIISWVIGMV VILFIALSYS
ELGSMFPEAG GMVKYTQYSH GSFIGFIAGW ANWIAIVSVI PVEAVASVQY MSSWPWEWAK
WTSGLVKNGT LTGEGLAFAS VLLLIYFLLN YWTVNLFSKA NSLITIFKII IPGLTIGALL
FVGFHGENFT GGQSIAPNGW ASVLTAVATS GIVFAFNGFQ SPINMAGEAK NPGKSIPIAV
VGSLFVATVI YVLLQIAFIG AVNPSDIAHG WSHLNFNSPF ADLAIALNIN WLVIVLYADA
FVSPSGTGIT YTATTSRMIY GMEKNKYMPS IFGKLHPIYG VPRQAMFFNL IVSFIFLFLF
RGWGVLAEII SVATLISYIT GPITVMTLRR TGKDLYRPLR LKGLNVIAPL GFIFASLVLY
WARWPLTGQV LFIILIGLPI YFYYQAKAKW KGFGRNFKAG VWMVFYLLAM MVISYLGSDK
FGGLNVIHYG WDMVLIAMVS LVFYVWALKS GYQTEYLKDA KEINSQLLNG QSEAAAGKE
