CATIP_XENLA
ID CATIP_XENLA Reviewed; 376 AA.
AC Q0IHI3;
DT 02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 42.
DE RecName: Full=Ciliogenesis-associated TTC17-interacting protein;
GN Name=catip;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in primary ciliogenesis by modulating actin
CC polymerization. {ECO:0000250|UniProtKB:Q7Z7H3}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q7Z7H3}. Cytoplasm
CC {ECO:0000250|UniProtKB:Q7Z7H3}. Cell membrane
CC {ECO:0000250|UniProtKB:Q7Z7H3}. Cytoplasm, cytoskeleton
CC {ECO:0000250|UniProtKB:Q7Z7H3}.
CC -!- SIMILARITY: Belongs to the CATIP family. {ECO:0000305}.
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DR EMBL; BC123143; AAI23144.1; -; mRNA.
DR RefSeq; NP_001090309.1; NM_001096840.1.
DR AlphaFoldDB; Q0IHI3; -.
DR PRIDE; Q0IHI3; -.
DR GeneID; 779218; -.
DR KEGG; xla:779218; -.
DR CTD; 779218; -.
DR Xenbase; XB-GENE-942709; catip.L.
DR OrthoDB; 998907at2759; -.
DR Proteomes; UP000186698; Chromosome 9_10L.
DR Bgee; 779218; Expressed in testis and 8 other tissues.
DR GO; GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR GO; GO:0030041; P:actin filament polymerization; ISS:UniProtKB.
DR GO; GO:0044782; P:cilium organization; ISS:UniProtKB.
PE 2: Evidence at transcript level;
KW Cell membrane; Cilium biogenesis/degradation; Cytoplasm; Cytoskeleton;
KW Membrane; Nucleus; Reference proteome.
FT CHAIN 1..376
FT /note="Ciliogenesis-associated TTC17-interacting protein"
FT /id="PRO_0000391709"
FT REGION 355..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 376 AA; 41982 MW; 9E4A0C20E94F2358 CRC64;
MEPENAQGKS PAENEQEVVP DVASAMSASS EALEFLCSVG LEELNLCLFT DSLATVSVSG
VELGNFAVSV QPAYYQLDGL EEEKCFLVHA ASQGTIDGVP CGTSIIGHIS YKLETLEQHV
HEYVKLKGHS LDKKTQIVRQ GDKLVINRII TEGEKLHRET SSHSTSLLSG LISEAANLLI
MRILARRKIK DPLKFLAFDE EGNLCTSTYA PLGSQAQVIG KEMVDVFGIE RTIHSPEVPT
TWQCFFLSDG HLASHVQIGS PVTIKLNEMP VLSEPDEKDP KPVFEKKPLA WQEDLQLHSE
FLDRKEELIS DHETYLRRHP EVKVLLADFM QFLLLRKPDD IMDFAAEYFK PFSSTQEPND
PFVSSHHASP FRNVSH