YBEH_ECOLI
ID YBEH_ECOLI Reviewed; 75 AA.
AC P0DP63; P39874; P77104; P77192;
DT 05-JUL-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2017, sequence version 1.
DT 25-MAY-2022, entry version 15.
DE RecName: Full=Putative protein YbeH;
GN Name=ybeH; OrderedLocusNames=b4581, JW0620; ORFNames=b0625;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-52.
RC STRAIN=K12;
RX PubMed=7984109; DOI=10.1111/j.1365-2958.1994.tb00424.x;
RA Yamanaka K., Mitani T., Ogura T., Niki H., Hiraga S.;
RT "Cloning, sequencing, and characterization of multicopy suppressors of a
RT mukB mutation in Escherichia coli.";
RL Mol. Microbiol. 13:301-312(1994).
RN [6]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 31-75.
RC STRAIN=K12 / EMG2;
RA Robison K., O'Keeffe T., Church G.M.;
RL Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Pseudogene resulting from a nucleotide deletion that
CC introduces a premature stop codon at position 66. This is the N-
CC terminal fragment. The intact protein (AC A0A140NCB4) hydrolyzes
CC deaminated glutathione (dGSH, 2-oxoglutaramate) to alpha-ketoglutarate
CC (alpha-KG) and cysteinylglycine, has less activity against alpha-
CC ketoglutaramate (a-KGM) and no activity on glutathione or L-glutamine
CC (By similarity). May function as a metabolite repair enzyme (By
CC similarity). {ECO:0000250|UniProtKB:A0A140NCB4}.
CC -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily.
CC NIT1/NIT2 family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB40825.1; Type=Erroneous initiation; Note=Extended N-terminus.;
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DR EMBL; U82598; AAB40825.1; ALT_INIT; Genomic_DNA.
DR EMBL; U00096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AP009048; BAA35268.1; -; Genomic_DNA.
DR EMBL; D28497; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; U38811; AAA81032.1; -; Genomic_DNA.
DR PIR; G64796; G64796.
DR AlphaFoldDB; P0DP63; -.
DR SMR; P0DP63; -.
DR STRING; 316407.4062248; -.
DR EnsemblBacteria; BAA35268; BAA35268; BAA35268.
DR KEGG; ecj:JW0620; -.
DR eggNOG; COG0388; Bacteria.
DR HOGENOM; CLU_2579730_0_0_6; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR Gene3D; 3.60.110.10; -; 1.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR SUPFAM; SSF56317; SSF56317; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..75
FT /note="Putative protein YbeH"
FT /id="PRO_0000440694"
SQ SEQUENCE 75 AA; 7969 MW; 0A0497D95BF683EE CRC64;
MLVAAGQFAV TSVWEKNAEI CASLMAQAAE NDASLFALPE ALLARDDHDA DLSVKSAQLL
EGEFLGLYGE KVNVT
