ID   YBEY_BURTA              Reviewed;         437 AA.
AC   Q2T103;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Endoribonuclease YbeY;
DE            EC=3.1.-.-;
GN   Name=ybeY; OrderedLocusNames=BTH_I0589;
OS   Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 /
OS   E264).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=271848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264;
RX   PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA   Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA   DeShazer D.;
RT   "Bacterial genome adaptation to niches: divergence of the potential
RT   virulence genes in three Burkholderia species of different survival
RT   strategies.";
RL   BMC Genomics 6:174-174(2005).
CC   -!- FUNCTION: Single strand-specific metallo-endoribonuclease involved in
CC       late-stage 70S ribosome quality control and in maturation of the 3'
CC       terminus of the 16S rRNA. {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC       Note=Binds 1 zinc ion. {ECO:0000250};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the endoribonuclease YbeY family. {ECO:0000305}.
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DR   EMBL; CP000086; ABC39120.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2T103; -.
DR   SMR; Q2T103; -.
DR   PRIDE; Q2T103; -.
DR   EnsemblBacteria; ABC39120; ABC39120; BTH_I0589.
DR   KEGG; bte:BTH_I0589; -.
DR   HOGENOM; CLU_626548_0_0_4; -.
DR   Proteomes; UP000001930; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.390.30; -; 1.
DR   HAMAP; MF_00009; Endoribonucl_YbeY; 1.
DR   InterPro; IPR023091; MetalPrtase_cat_dom_sf_prd.
DR   InterPro; IPR002036; YbeY.
DR   InterPro; IPR020549; YbeY_CS.
DR   PANTHER; PTHR46986; PTHR46986; 1.
DR   Pfam; PF02130; YbeY; 1.
DR   TIGRFAMs; TIGR00043; TIGR00043; 1.
DR   PROSITE; PS01306; UPF0054; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Endonuclease; Hydrolase; Metal-binding; Nuclease;
KW   Ribosome biogenesis; rRNA processing; Zinc.
FT   CHAIN           1..437
FT                   /note="Endoribonuclease YbeY"
FT                   /id="PRO_0000284177"
FT   REGION          1..172
FT                   /note="Unknown"
FT   REGION          64..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          173..437
FT                   /note="Endoribonuclease YbeY"
FT   BINDING         399
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
FT   BINDING         403
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
FT   BINDING         409
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   437 AA;  47549 MW;  EF59E431A6900854 CRC64;
     MRATGRARGA RRPLRVVRRP GCPVTRPNRP VHQSIGPTSR LARVDVHPSA CAVSIEIAPL
     AARGRRNTDP AGTPLADSAP LRQPLRSVRA HRFGIRAMTR GRAITRTSNE PSSHAGHASP
     KPPANHRPGR RPTSTPNRRA PAPPPSATPR ETPSGRSSVW CILNRVQTDV NVMKSSRSSK
     SARAEAAQPE FPRLSLFDAK GKVKTVEAQA LRVDFADGRS LMFDLSGSSG DAAVAIVAQH
     TDPSLRATIA LRPEHYDSVT VEAGADENPD FAHDATDDAG EDAPNREPEL DLAVQYGDEI
     GDAQRRSLPK RKVIAEWLEP AIFSDAQFTV RFVGADEGRT LNHSYRHKDY ATNVLTFAYG
     EEPDGVTVAD LVLCCPVVEK EAREQGKTLV AHYAHLLVHG ALHAQGYDHE RGEEDAAEME
     ALEIDILAKL GFPNPYR