ID   CATR_ACILW              Reviewed;         303 AA.
AC   O33945;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Probable cat1 operon transcriptional activator;
DE   AltName: Full=ORFR1;
OS   Acinetobacter lwoffii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter.
OX   NCBI_TaxID=28090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K24;
RX   PubMed=9473520; DOI=10.1006/bbrc.1997.7912;
RA   Kim S.I., Leem S.-H., Choi J.-S., Ha K.-S.;
RT   "Organization and transcriptional characterization of the cat1 gene cluster
RT   in Acinetobacter lwoffi K24.";
RL   Biochem. Biophys. Res. Commun. 243:289-294(1998).
CC   -!- FUNCTION: Probable positive regulator of the cat1 operon which encode
CC       enzymes responsible for the degradation of catechol to acetyl-CoA via
CC       the beta-ketoadipate pathway.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U77658; AAC46229.1; -; Genomic_DNA.
DR   PIR; JC5946; JC5946.
DR   AlphaFoldDB; O33945; -.
DR   SMR; O33945; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; Aromatic hydrocarbons catabolism; DNA-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..303
FT                   /note="Probable cat1 operon transcriptional activator"
FT                   /id="PRO_0000105600"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   303 AA;  34267 MW;  D0F7ABAA996D646F CRC64;
     MDLRQFRYFV AVARERNFTR AARQLNIAQP PLSRQIQLLE EEVGVPLLIR NSRPVQLTDA
     GRLFFEQAIQ VLGRVEQMQA ATRRVGLHQR SVLSIGFVAS TLYGVLPTLM RKLRQHAPEL
     DIQMVELMSV QQIQAINEGR IDIGFGRVHH SDPNVSSIVL HEERLAVALP MESPMAREST
     PLPVHQLAGE KLIVYPKEPR PGFADQVLNI LDRHDVQPGQ VMEVREIQTA LGLVAAEFGV
     CVIPASARQM RHDVHYRLID GDRATSPVIV SHRANDSSKY ISLTKQLIRE MYAEHPAWLD
     THN