ID   YBGC_HELPJ              Reviewed;         133 AA.
AC   Q9ZLX8;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Acyl-CoA thioesterase YbgC;
DE            EC=3.1.2.-;
GN   Name=ybgC; OrderedLocusNames=jhp_0448;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Thioesterase that may be involved in phospholipid metabolism.
CC       Displays acyl-CoA thioesterase activity with lauroyl-CoA (C12:0),
CC       myristoyl-CoA (C14:0), palmitoyl-CoA (C16:0), stearoyl-CoA (C18:0) and
CC       benzoyl-CoA, catalyzing the hydrolysis of the thioester bond. Has low
CC       activity with butyryl-CoA and octanoyl-CoA (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homotetramer. May interact with CagA (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
CC       {ECO:0000305}.
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DR   EMBL; AE001439; AAD06026.1; -; Genomic_DNA.
DR   PIR; E71930; E71930.
DR   RefSeq; WP_001203800.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZLX8; -.
DR   SMR; Q9ZLX8; -.
DR   STRING; 85963.jhp_0448; -.
DR   EnsemblBacteria; AAD06026; AAD06026; jhp_0448.
DR   KEGG; hpj:jhp_0448; -.
DR   PATRIC; fig|85963.30.peg.557; -.
DR   eggNOG; COG0824; Bacteria.
DR   OMA; FPIRVYW; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR008272; HB-CoA_thioesterase_AS.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR006683; Thioestr_dom.
DR   InterPro; IPR006684; YbgC/YbaW.
DR   Pfam; PF03061; 4HBT; 1.
DR   PIRSF; PIRSF003230; YbgC; 1.
DR   SUPFAM; SSF54637; SSF54637; 1.
DR   TIGRFAMs; TIGR00051; TIGR00051; 1.
DR   PROSITE; PS01328; 4HBCOA_THIOESTERASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Lipid metabolism.
FT   CHAIN           1..133
FT                   /note="Acyl-CoA thioesterase YbgC"
FT                   /id="PRO_0000087768"
FT   ACT_SITE        11
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10041"
SQ   SEQUENCE   133 AA;  15555 MW;  0A59784B96B802F9 CRC64;
     MRCRVYYEDT DSEGVVYHAN YLKYCERARS EFFFKQNVLP ENEEGVFVIR SIKADFFTPA
     SLGQVLEIRT QIKELRKVFV VLFQEIYCIQ NASLEPMKPF KVFASEIKFG FVNRSTYSPI
     AIPKLFKELL SAV