YBH4_SCHPO
ID YBH4_SCHPO Reviewed; 867 AA.
AC O59712;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Uncharacterized transporter C3B8.04c;
GN ORFNames=SPBC3B8.04c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC {ECO:0000305}.
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DR EMBL; CU329671; CAA18293.1; -; Genomic_DNA.
DR PIR; T40336; T40336.
DR RefSeq; NP_596410.1; NM_001022329.2.
DR AlphaFoldDB; O59712; -.
DR SMR; O59712; -.
DR BioGRID; 276810; 29.
DR STRING; 4896.SPBC3B8.04c.1; -.
DR iPTMnet; O59712; -.
DR MaxQB; O59712; -.
DR PaxDb; O59712; -.
DR PRIDE; O59712; -.
DR EnsemblFungi; SPBC3B8.04c.1; SPBC3B8.04c.1:pep; SPBC3B8.04c.
DR GeneID; 2540279; -.
DR KEGG; spo:SPBC3B8.04c; -.
DR PomBase; SPBC3B8.04c; -.
DR VEuPathDB; FungiDB:SPBC3B8.04c; -.
DR eggNOG; KOG1281; Eukaryota.
DR HOGENOM; CLU_005170_8_0_1; -.
DR InParanoid; O59712; -.
DR OMA; QLEHIFG; -.
DR PhylomeDB; O59712; -.
DR PRO; PR:O59712; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0098656; P:anion transmembrane transport; IBA:GO_Central.
DR GO; GO:0035435; P:phosphate ion transmembrane transport; ISO:PomBase.
DR GO; GO:0006817; P:phosphate ion transport; IBA:GO_Central.
DR GO; GO:0006797; P:polyphosphate metabolic process; IBA:GO_Central.
DR InterPro; IPR001898; SLC13A/DASS.
DR InterPro; IPR004331; SPX_dom.
DR Pfam; PF00939; Na_sulph_symp; 1.
DR Pfam; PF03105; SPX; 2.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..867
FT /note="Uncharacterized transporter C3B8.04c"
FT /id="PRO_0000303946"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 434..454
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 485..505
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 537..557
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 576..596
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 616..636
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 656..676
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 683..703
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 712..732
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 755..775
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 797..817
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 842..862
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 1..294
FT /note="SPX"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00714"
FT REGION 105..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..223
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 867 AA; 97050 MW; F24FAF97D323E556 CRC64;
MKFSHSLQFN AVPEWSESYI AYSNLKKLIY SLEHEQITLQ QGAPDEETRL LEHERRSPDD
RFMFALDKEL QGIVEFYAPK EKEIADQYGR IKGEFETYEN EYMSQGNNIN YPTPERLQKS
SASRKSGRMA RSQELPRITS SNREIYLNGQ TSDGGYAAPA ISRAESTAIQ PSEPHDVDTS
KNGLSKKQHS EAQPEVQGND DEVEEEDDDD DDEDEDEDED EDNNNNNRWL LIEQYPSDIV
AYENFVSLKR KLTQLYVSIH DLISYVHLNY TGFSKILKKY DKTLGSSLRE SYMKRVNQAY
PFLPATGKTL SKRLNIVAEW YAKLCCQGDT FVAIRRLRGH LREYVAWERN TIWREMMAME
RRTQAARLSG LKPVAADEKE SEQPPYFTIK TKFGVFRIPR CFFNSTIATL ITIIVIFILL
LSFPVIDNRE QNNCLALLVM VSLLWATEAI PLFVTSFLVP FMTVFLKILR DENGSPLSGK
ESTKVIFSSM WNPTIVLLLG GFTIAAALSK YHIAKRLATS ILAHAGRKPR SVLLTNMFVA
MFASMWISNV AAPVLCFSII QPLLRNLPAE SDFAKILIVG IALASNVGGI ASPISSPQNI
VALQNMDPAA GWGEWFAVSI PVSLLCIFSI WFLLSFGLLK DEHITLAKIR STKDTFTGVQ
WFISIVTIGT IVLWCLERRF DEVFGDMGVI ALVPIIVFFG TGLLTKEDFN NFLWTVIVLA
MGGVALGKVV SSSGLLELIA LKIGNAVSSL NTFRVLLIFS ALTLVVSSFI SHIVAAMVVL
PIVHEVGSRL ADPHPRLFVL ASGMMCSLAM ALPTSGFPNM TAIMMENEAG KRYLKVSDFL
KAGIPATLIS FVILLLIGTP IMRALGF
