YBHB_ECOLI
ID YBHB_ECOLI Reviewed; 158 AA.
AC P12994; P75766; Q2MBJ6;
DT 01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 155.
DE RecName: Full=UPF0098 protein YbhB;
GN Name=ybhB; OrderedLocusNames=b0773, JW0756;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3058702; DOI=10.1016/s0021-9258(19)77675-3;
RA Otsuka A.J., Buoncristiani M.R., Howard P.K., Flamm J., Johnson O.,
RA Yamamoto R., Uchida K., Cook C., Ruppert J., Matsuzaki J.;
RT "The Escherichia coli biotin biosynthetic enzyme sequences predicted from
RT the nucleotide sequence of the bio operon.";
RL J. Biol. Chem. 263:19577-19585(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP X-RAY CRYSTALLOGRAPHY (1.66 ANGSTROMS), AND CHARACTERIZATION.
RX PubMed=11439028; DOI=10.1006/jmbi.2001.4784;
RA Serre L., Pereira de Jesus K., Zelwer C., Bureaud N., Schoentgen F.,
RA Benedetti H.;
RT "Crystal structures of YBHB and YBCL from Escherichia coli, two bacterial
RT homologues to a Raf kinase inhibitor protein.";
RL J. Mol. Biol. 310:617-634(2001).
CC -!- SUBUNIT: Homodimer.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- SIMILARITY: Belongs to the UPF0098 family. {ECO:0000305}.
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DR EMBL; J04423; AAA23513.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73860.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76360.1; -; Genomic_DNA.
DR PIR; E64813; Q3ECBA.
DR RefSeq; NP_415294.1; NC_000913.3.
DR RefSeq; WP_000767389.1; NZ_STEB01000028.1.
DR PDB; 1FJJ; X-ray; 1.66 A; A=1-158.
DR PDB; 1VI3; X-ray; 1.76 A; A=2-158.
DR PDBsum; 1FJJ; -.
DR PDBsum; 1VI3; -.
DR AlphaFoldDB; P12994; -.
DR SMR; P12994; -.
DR BioGRID; 4261840; 25.
DR IntAct; P12994; 6.
DR STRING; 511145.b0773; -.
DR jPOST; P12994; -.
DR PaxDb; P12994; -.
DR PRIDE; P12994; -.
DR EnsemblBacteria; AAC73860; AAC73860; b0773.
DR EnsemblBacteria; BAE76360; BAE76360; BAE76360.
DR GeneID; 66670956; -.
DR GeneID; 945383; -.
DR KEGG; ecj:JW0756; -.
DR KEGG; eco:b0773; -.
DR PATRIC; fig|1411691.4.peg.1505; -.
DR EchoBASE; EB1220; -.
DR eggNOG; COG1881; Bacteria.
DR HOGENOM; CLU_083918_2_0_6; -.
DR InParanoid; P12994; -.
DR OMA; LAWDEVP; -.
DR PhylomeDB; P12994; -.
DR BioCyc; EcoCyc:EG11238-MON; -.
DR EvolutionaryTrace; P12994; -.
DR PRO; PR:P12994; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00865; PEBP_bact_arch; 1.
DR Gene3D; 3.90.280.10; -; 1.
DR InterPro; IPR008914; PEBP.
DR InterPro; IPR036610; PEBP-like_sf.
DR InterPro; IPR005247; YbhB_YbcL.
DR PANTHER; PTHR30289; PTHR30289; 1.
DR Pfam; PF01161; PBP; 1.
DR SUPFAM; SSF49777; SSF49777; 1.
DR TIGRFAMs; TIGR00481; TIGR00481; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Reference proteome.
FT CHAIN 1..158
FT /note="UPF0098 protein YbhB"
FT /id="PRO_0000137900"
FT CONFLICT 136
FT /note="G -> A (in Ref. 1; AAA23513)"
FT /evidence="ECO:0000305"
FT STRAND 2..4
FT /evidence="ECO:0007829|PDB:1FJJ"
FT HELIX 16..18
FT /evidence="ECO:0007829|PDB:1FJJ"
FT STRAND 34..37
FT /evidence="ECO:0007829|PDB:1FJJ"
FT STRAND 45..52
FT /evidence="ECO:0007829|PDB:1FJJ"
FT TURN 56..59
FT /evidence="ECO:0007829|PDB:1FJJ"
FT STRAND 61..70
FT /evidence="ECO:0007829|PDB:1FJJ"
FT HELIX 80..82
FT /evidence="ECO:0007829|PDB:1FJJ"
FT STRAND 99..102
FT /evidence="ECO:0007829|PDB:1FJJ"
FT STRAND 114..126
FT /evidence="ECO:0007829|PDB:1FJJ"
FT HELIX 136..146
FT /evidence="ECO:0007829|PDB:1FJJ"
FT STRAND 147..157
FT /evidence="ECO:0007829|PDB:1FJJ"
SQ SEQUENCE 158 AA; 17085 MW; 0AD6F21157060A4C CRC64;
MKLISNDLRD GDKLPHRHVF NGMGYDGDNI SPHLAWDDVP AGTKSFVVTC YDPDAPTGSG
WWHWVVVNLP ADTRVLPQGF GSGLVAMPDG VLQTRTDFGK TGYDGAAPPK GETHRYIFTV
HALDIERIDV DEGASGAMVG FNVHFHSLAS ASITAMFS
