YBHD_ECOLI
ID YBHD_ECOLI Reviewed; 317 AA.
AC P52696; P75761;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 27-APR-2001, sequence version 3.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator YbhD;
GN Name=ybhD; OrderedLocusNames=b0768, JW5896;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 210-317.
RC STRAIN=K12;
RA Shanmugam K.T.;
RL Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION.
RA Robison K.;
RL Unpublished observations (DEC-1995).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA35432.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; U00096; AAC73855.2; -; Genomic_DNA.
DR EMBL; AP009048; BAA35432.1; ALT_INIT; Genomic_DNA.
DR EMBL; U27192; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; H64812; H64812.
DR RefSeq; NP_415289.4; NC_000913.3.
DR RefSeq; WP_001350493.1; NZ_LN832404.1.
DR AlphaFoldDB; P52696; -.
DR SMR; P52696; -.
DR BioGRID; 4261144; 2.
DR STRING; 511145.b0768; -.
DR PaxDb; P52696; -.
DR PRIDE; P52696; -.
DR EnsemblBacteria; AAC73855; AAC73855; b0768.
DR EnsemblBacteria; BAA35432; BAA35432; BAA35432.
DR GeneID; 944869; -.
DR KEGG; ecj:JW5896; -.
DR KEGG; eco:b0768; -.
DR PATRIC; fig|1411691.4.peg.1510; -.
DR EchoBASE; EB3019; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_0_6; -.
DR InParanoid; P52696; -.
DR OMA; KQCVIAD; -.
DR PhylomeDB; P52696; -.
DR BioCyc; EcoCyc:G6398-MON; -.
DR PRO; PR:P52696; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..317
FT /note="Uncharacterized HTH-type transcriptional regulator
FT YbhD"
FT /id="PRO_0000105780"
FT DOMAIN 1..60
FT /note="HTH lysR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT DNA_BIND 20..40
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ SEQUENCE 317 AA; 36058 MW; 8B02C4808B4665D2 CRC64;
MKHELSSMKA FVILAESSSF NNAAKLLNIT QPALTRRIKK MEEDLHVQLF ERTTRKVTLT
KAGKRLLPEA RELIKKFDET LFNIRDMNAY HRGMVTLACI PTAVFYFLPL AIGKFNELYP
NIKVRILEQG TNNCMESVLC NESDFGINMN NVTNSSIDFT PLVNEPFVLA CRRDHPLAKK
QLVEWQELVG YKMIGVRSSS GNRLLIEQQL ADKPWKLDWF YEVRHLSTSL GLVEAGLGIS
ALPGLAMPHA PYSSIIGIPL VEPVIRRTLG IIRRKDAVLS PAAERFFALL INLWTDDKDN
LWTNIVERQR HALQEIG