ID   YBHG_ECOLI              Reviewed;         332 AA.
AC   P75777;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 136.
DE   RecName: Full=UPF0194 membrane protein YbhG {ECO:0000255|HAMAP-Rule:MF_01304, ECO:0000305};
DE   Flags: Precursor;
GN   Name=ybhG; OrderedLocusNames=b0795, JW0779;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   FUNCTION, INDUCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=27112147; DOI=10.1099/mic.0.000292;
RA   Yamanaka Y., Shimada T., Yamamoto K., Ishihama A.;
RT   "Transcription factor CecR (YbiH) regulates a set of genes affecting the
RT   sensitivity of Escherichia coli against cefoperazone and chloramphenicol.";
RL   Microbiology 162:1253-1264(2016).
CC   -!- FUNCTION: Could be involved in the sensitivity control to
CC       chloramphenicol. {ECO:0000305|PubMed:27112147}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_01304,
CC       ECO:0000305}.
CC   -!- INDUCTION: Repressed by the transcriptional regulator CecR.
CC       {ECO:0000269|PubMed:27112147}.
CC   -!- DISRUPTION PHENOTYPE: Mutant shows increased sensitivity to
CC       chloramphenicol. {ECO:0000269|PubMed:27112147}.
CC   -!- SIMILARITY: Belongs to the UPF0194 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01304, ECO:0000305}.
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DR   EMBL; U00096; AAC73882.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA35455.1; -; Genomic_DNA.
DR   PIR; C64816; C64816.
DR   RefSeq; NP_415316.1; NC_000913.3.
DR   RefSeq; WP_000976409.1; NZ_CP011343.2.
DR   AlphaFoldDB; P75777; -.
DR   SMR; P75777; -.
DR   BioGRID; 4259960; 169.
DR   BioGRID; 849788; 1.
DR   IntAct; P75777; 1.
DR   STRING; 511145.b0795; -.
DR   TCDB; 3.A.1.105.15; the atp-binding cassette (abc) superfamily.
DR   jPOST; P75777; -.
DR   PaxDb; P75777; -.
DR   PRIDE; P75777; -.
DR   EnsemblBacteria; AAC73882; AAC73882; b0795.
DR   EnsemblBacteria; BAA35455; BAA35455; BAA35455.
DR   GeneID; 945414; -.
DR   KEGG; ecj:JW0779; -.
DR   KEGG; eco:b0795; -.
DR   PATRIC; fig|511145.12.peg.821; -.
DR   EchoBASE; EB3099; -.
DR   eggNOG; COG0845; Bacteria.
DR   HOGENOM; CLU_018816_6_3_6; -.
DR   InParanoid; P75777; -.
DR   OMA; AYPDQVF; -.
DR   PhylomeDB; P75777; -.
DR   BioCyc; EcoCyc:G6412-MON; -.
DR   PRO; PR:P75777; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0046677; P:response to antibiotic; IDA:EcoCyc.
DR   HAMAP; MF_01304; UPF0194; 1.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR022936; UPF0194_membrane_YbhG.
DR   Pfam; PF16576; HlyD_D23; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01304"
FT   CHAIN           21..332
FT                   /note="UPF0194 membrane protein YbhG"
FT                   /id="PRO_0000088746"
FT   COILED          145..207
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01304"
SQ   SEQUENCE   332 AA;  36416 MW;  A61DC1D96F84785E CRC64;
     MMKKPVVIGL AVVVLAAVVA GGYWWYQSRQ DNGLTLYGNV DIRTVNLSFR VGGRVESLAV
     DEGDAIKAGQ VLGELDHKPY EIALMQAKAG VSVAQAQYDL MLAGYRNEEI AQAAAAVKQA
     QAAYDYAQNF YNRQQGLWKS RTISANDLEN ARSSRDQAQA TLKSAQDKLR QYRSGNREQD
     IAQAKASLEQ AQAQLAQAEL NLQDSTLIAP SDGTLLTRAV EPGTVLNEGG TVFTVSLTRP
     VWVRAYVDER NLDQAQPGRK VLLYTDGRPD KPYHGQIGFV SPTAEFTPKT VETPDLRTDL
     VYRLRIVVTD ADDALRQGMP VTVQFGDEAG HE