YBI6_YEAST
ID YBI6_YEAST Reviewed; 466 AA.
AC P38177; D6VPR8; Q6B2T6;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Uncharacterized protein YBL086C;
GN OrderedLocusNames=YBL086C; ORFNames=YBL0714;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7502586; DOI=10.1002/yea.320111112;
RA Obermaier B., Gassenhuber J., Piravandi E., Domdey H.;
RT "Sequence analysis of a 78.6 kb segment of the left end of Saccharomyces
RT cerevisiae chromosome II.";
RL Yeast 11:1103-1112(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7813418; DOI=10.1002/j.1460-2075.1994.tb06923.x;
RA Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C.,
RA Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M.,
RA Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M.,
RA Cziepluch C., Demolis N., Delaveau T., Doignon F., Domdey H.,
RA Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D.,
RA Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N.,
RA Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J.,
RA Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C.,
RA Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P.,
RA Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y.,
RA Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F.,
RA Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E.,
RA Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M.,
RA Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B.,
RA Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L.,
RA Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M.,
RA Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S.,
RA Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K.,
RA Mewes H.-W., Kleine K.;
RT "Complete DNA sequence of yeast chromosome II.";
RL EMBO J. 13:5795-5809(1994).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-433, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=17287358; DOI=10.1073/pnas.0607084104;
RA Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,
RA Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.;
RT "Analysis of phosphorylation sites on proteins from Saccharomyces
RT cerevisiae by electron transfer dissociation (ETD) mass spectrometry.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007).
RN [7]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-433 AND SER-439, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
CC -!- MISCELLANEOUS: Present with 396 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: To S.pombe SpCC1494.08c. {ECO:0000305}.
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DR EMBL; X79489; CAA56019.1; -; Genomic_DNA.
DR EMBL; Z35847; CAA84907.1; -; Genomic_DNA.
DR EMBL; AY692644; AAT92663.1; -; Genomic_DNA.
DR EMBL; BK006936; DAA07038.1; -; Genomic_DNA.
DR PIR; S45419; S45419.
DR RefSeq; NP_009467.1; NM_001178326.1.
DR AlphaFoldDB; P38177; -.
DR BioGRID; 32618; 100.
DR DIP; DIP-3948N; -.
DR IntAct; P38177; 2.
DR MINT; P38177; -.
DR STRING; 4932.YBL086C; -.
DR iPTMnet; P38177; -.
DR MaxQB; P38177; -.
DR PaxDb; P38177; -.
DR PRIDE; P38177; -.
DR EnsemblFungi; YBL086C_mRNA; YBL086C; YBL086C.
DR GeneID; 852192; -.
DR KEGG; sce:YBL086C; -.
DR SGD; S000000182; YBL086C.
DR VEuPathDB; FungiDB:YBL086C; -.
DR eggNOG; ENOG502R9IN; Eukaryota.
DR HOGENOM; CLU_036649_0_0_1; -.
DR InParanoid; P38177; -.
DR OMA; GYCYVKW; -.
DR BioCyc; YEAST:G3O-28975-MON; -.
DR PRO; PR:P38177; -.
DR Proteomes; UP000002311; Chromosome II.
DR RNAct; P38177; protein.
DR InterPro; IPR039931; FAM102-like.
DR InterPro; IPR019448; NT-C2.
DR PANTHER; PTHR21456; PTHR21456; 1.
DR Pfam; PF10358; NT-C2; 1.
DR PROSITE; PS51840; C2_NT; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..466
FT /note="Uncharacterized protein YBL086C"
FT /id="PRO_0000202445"
FT DOMAIN 4..199
FT /note="C2 NT-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01186"
FT REGION 262..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 400..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..452
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 433
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17287358,
FT ECO:0007744|PubMed:19779198"
FT MOD_RES 439
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19779198"
FT CONFLICT 318
FT /note="W -> R (in Ref. 4; AAT92663)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 466 AA; 51997 MW; 926CD2E94E792C6B CRC64;
MPFNHNSKAK RPKFLLDLQI KELVNIPQSS GYCYTKWRLK DGTGTSGHKV ALDGEHQTTS
TQSRGTTKHV HVQHHRAQWN YSLDKPILVK LHLDKNGRFL KKILVLDVFF EFADANSSLT
SSSSPNGKVK KTTYANATAL TATGNNSYSQ KITGKLLLGT VDIDITEYVK EDETPTTNRF
LLKHSKVNSI INVSLQLKLV RGSYEDFNIS KSFTNGQLAN YRPGINTILD NTSELSSPTS
TTNQMSPKNT FSNFNGIGTT VAKPGTNATG NSTSIKSPTS TNHKSSEMTT KPGLSTTISS
SMSPLIESLY QKTFKLPWDP RPGEFTPREC VEDILQGGNG WAKNEKGINL IDLQALRLNE
MEEEYYNPNY GNNLGNKASS WPPNPSDDGY STMGKREYLE KKQNWSHMSR AQRAKLRTHN
DEDNENTAND KGSDKDNNSV EDNNPTDFLT DRIRENKNWS IITPSG
