ID   YBIS_ECO57              Reviewed;         306 AA.
AC   P0AAY0; P75789;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Probable L,D-transpeptidase YbiS;
DE            EC=2.-.-.-;
DE   Flags: Precursor;
GN   Name=ybiS; OrderedLocusNames=Z1041, ECs0896;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Responsible, at least in part, for anchoring of the major
CC       outer membrane lipoprotein (Lpp) to the peptidoglycan via a meso-
CC       diaminopimelyl-L-Lys- bond on the terminal residue of Lpp.
CC       {ECO:0000250}.
CC   -!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the YkuD family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG55191.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34319.1; -; Genomic_DNA.
DR   PIR; C85591; C85591.
DR   PIR; H90740; H90740.
DR   RefSeq; NP_308923.1; NC_002695.1.
DR   RefSeq; WP_001056384.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AAY0; -.
DR   SMR; P0AAY0; -.
DR   STRING; 155864.EDL933_0942; -.
DR   MEROPS; C82.A04; -.
DR   PRIDE; P0AAY0; -.
DR   EnsemblBacteria; AAG55191; AAG55191; Z1041.
DR   EnsemblBacteria; BAB34319; BAB34319; ECs_0896.
DR   GeneID; 66670908; -.
DR   GeneID; 917644; -.
DR   KEGG; ece:Z1041; -.
DR   KEGG; ecs:ECs_0896; -.
DR   PATRIC; fig|386585.9.peg.1011; -.
DR   eggNOG; COG1376; Bacteria.
DR   HOGENOM; CLU_046834_0_1_6; -.
DR   OMA; QNRSGMP; -.
DR   UniPathway; UPA00219; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071972; F:peptidoglycan L,D-transpeptidase activity; IEA:UniProt.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   CDD; cd16913; YkuD_like; 1.
DR   Gene3D; 2.40.440.10; -; 1.
DR   InterPro; IPR005490; LD_TPept_cat_dom.
DR   InterPro; IPR041597; Ldt_C.
DR   InterPro; IPR038063; Transpep_catalytic_dom.
DR   Pfam; PF17969; Ldt_C; 1.
DR   Pfam; PF03734; YkuD; 1.
DR   SUPFAM; SSF141523; SSF141523; 1.
PE   3: Inferred from homology;
KW   Cell shape; Cell wall biogenesis/degradation; Glycosyltransferase;
KW   Hydrolase; Peptidoglycan synthesis; Periplasm; Reference proteome; Signal;
KW   Transferase.
FT   SIGNAL          1..24
FT   CHAIN           25..306
FT                   /note="Probable L,D-transpeptidase YbiS"
FT                   /id="PRO_0000042566"
SQ   SEQUENCE   306 AA;  33325 MW;  4D9DDED8B0ACD69F CRC64;
     MNMKLKTLFA AAFAVVGFCS TASAVTYPLP TDGSRLVGQN QVITIPEGNT QPLEYFAAEY
     QMGLSNMMEA NPGVDTFLPK GGTVLNIPQQ LILPDTVHEG IVINSAEMRL YYYPKGTNTV
     IVLPIGIGQL GKDTPINWTT KVERKKAGPT WTPTAKMHAE YRAAGEPLPA VVPAGPDNPM
     GLYALYIGRL YAIHGTNANF GIGLRVSHGC VRLRNEDIKF LFEKVPVGTR VQFIDEPVKA
     TTEPDGSRYI EVHNPLSTTE AQFEGQEIVP ITLTKSVQTV TGQPDVDQVV LDEAIKNRSG
     MPVRLN