ID   YBIT_ECOL6              Reviewed;         530 AA.
AC   P0A9U4; P75790;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Probable ATP-binding protein YbiT;
GN   Name=ybiT; OrderedLocusNames=c0906;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
RN   [2]
RP   FAMILY, DISRUPTION PHENOTYPE, AND MUTAGENESIS OF GLU-181 AND GLU-464.
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=30597160; DOI=10.1016/j.jmb.2018.12.013;
RA   Murina V., Kasari M., Takada H., Hinnu M., Saha C.K., Grimshaw J.W.,
RA   Seki T., Reith M., Putrins M., Tenson T., Strahl H., Hauryliuk V.,
RA   Atkinson G.C.;
RT   "ABCF ATPases involved in protein synthesis, ribosome assembly and
RT   antibiotic resistance: structural and functional diversification across the
RT   tree of life.";
RL   J. Mol. Biol. 431:3568-3590(2019).
CC   -!- DISRUPTION PHENOTYPE: No visible growth or ribosome-associated
CC       phenotype. {ECO:0000269|PubMed:30597160}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCF family.
CC       YbiT subfamily. {ECO:0000303|PubMed:30597160}.
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DR   EMBL; AE014075; AAN79379.1; -; Genomic_DNA.
DR   RefSeq; WP_000961458.1; NC_004431.1.
DR   AlphaFoldDB; P0A9U4; -.
DR   SMR; P0A9U4; -.
DR   STRING; 199310.c0906; -.
DR   EnsemblBacteria; AAN79379; AAN79379; c0906.
DR   GeneID; 66670907; -.
DR   KEGG; ecc:c0906; -.
DR   eggNOG; COG0488; Bacteria.
DR   HOGENOM; CLU_000604_36_0_6; -.
DR   OMA; DWMGQWT; -.
DR   BioCyc; ECOL199310:C0906-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR032781; ABC_tran_Xtn.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   Pfam; PF12848; ABC_tran_Xtn; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   1: Evidence at protein level;
KW   ATP-binding; Nucleotide-binding; Repeat.
FT   CHAIN           1..530
FT                   /note="Probable ATP-binding protein YbiT"
FT                   /id="PRO_0000093160"
FT   DOMAIN          2..252
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          320..526
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         34..41
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         352..359
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   MUTAGEN         181
FT                   /note="E->Q: Causes growth defect at 18 degrees Celsius in
FT                   bipA deletion strain; when associated with Q-464 (called
FT                   EQ2)."
FT                   /evidence="ECO:0000269|PubMed:30597160"
FT   MUTAGEN         464
FT                   /note="E->Q: Causes growth defect at 18 degrees Celsius in
FT                   bipA deletion strain; when associated with Q-181 (EQ2)."
FT                   /evidence="ECO:0000269|PubMed:30597160"
SQ   SEQUENCE   530 AA;  59858 MW;  EE75D66B5A58729A CRC64;
     MLVSSNVTMQ FGSKPLFENI SVKFGGGNRY GLIGANGSGK STFMKILGGD LEPTLGNVSL
     DPNERIGKLR QDQFAFEEFT VLDTVIMGHK ELWEVKQERD RIYALPEMSE EDGYKVADLE
     VKYGEMDGYS AEARAGELLL GVGIPVEQHY GPMSEVAPGW KLRVLLAQAL FADPDILLLD
     EPTNNLDIDT IRWLEQVLNE RDSTMIIISH DRHFLNMVCT HMADLDYGEL RVYPGNYDEY
     MTAATQARER LLADNAKKKA QIAELQSFVS RFSANASKSR QATSRARQID KIKLEEVKAS
     SRQNPFIRFE QDKKLFRNAL EVEGLTKGFD NGPLFKNLNL LLEVGEKLAV LGTNGVGKST
     LLKTLVGDLQ PDSGTVKWSE NARIGYYAQD HEYEFENDLT VFEWMSQWKQ EGDDEQAVRS
     ILGRLLFSQD DIKKPAKVLS GGEKGRMLFG KLMMQKPNIL IMDEPTNHLD MESIESLNMA
     LELYQGTLIF VSHDREFVSS LATRILEITP ERVIDFSGNY EDYLRSKGIE