YBU1_SCHPO
ID YBU1_SCHPO Reviewed; 1157 AA.
AC O94525;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Uncharacterized ribonuclease C609.01;
DE EC=3.1.-.-;
GN ORFNames=SPBC609.01;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the RNR ribonuclease family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329671; CAA22830.1; -; Genomic_DNA.
DR PIR; T40572; T40572.
DR RefSeq; NP_596311.1; NM_001022233.2.
DR AlphaFoldDB; O94525; -.
DR SMR; O94525; -.
DR BioGRID; 277356; 2.
DR STRING; 4896.SPBC609.01.1; -.
DR iPTMnet; O94525; -.
DR MaxQB; O94525; -.
DR PaxDb; O94525; -.
DR PRIDE; O94525; -.
DR EnsemblFungi; SPBC609.01.1; SPBC609.01.1:pep; SPBC609.01.
DR GeneID; 2540838; -.
DR KEGG; spo:SPBC609.01; -.
DR PomBase; SPBC609.01; -.
DR VEuPathDB; FungiDB:SPBC609.01; -.
DR eggNOG; KOG2102; Eukaryota.
DR HOGENOM; CLU_278744_0_0_1; -.
DR InParanoid; O94525; -.
DR OMA; YTHFCHP; -.
DR PhylomeDB; O94525; -.
DR PRO; PR:O94525; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0000178; C:exosome (RNase complex); IBA:GO_Central.
DR GO; GO:0000932; C:P-body; ISS:PomBase.
DR GO; GO:0000175; F:3'-5'-exoribonuclease activity; ISO:PomBase.
DR GO; GO:0003723; F:RNA binding; ISM:PomBase.
DR GO; GO:0006402; P:mRNA catabolic process; IBA:GO_Central.
DR GO; GO:0000291; P:nuclear-transcribed mRNA catabolic process, exonucleolytic; ISO:PomBase.
DR GO; GO:0036450; P:polyuridylation-dependent decapping of nuclear-transcribed mRNA; ISS:PomBase.
DR Gene3D; 2.40.50.140; -; 1.
DR InterPro; IPR041505; Dis3_CSD2.
DR InterPro; IPR041093; Dis3l2_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR001900; RNase_II/R.
DR Pfam; PF17877; Dis3l2_C_term; 1.
DR Pfam; PF17849; OB_Dis3; 1.
DR Pfam; PF00773; RNB; 1.
DR SMART; SM00955; RNB; 1.
DR SUPFAM; SSF50249; SSF50249; 2.
PE 3: Inferred from homology;
KW Cytoplasm; Hydrolase; Nuclease; Reference proteome.
FT CHAIN 1..1157
FT /note="Uncharacterized ribonuclease C609.01"
FT /id="PRO_0000314758"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1084..1113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1084..1108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1157 AA; 128576 MW; 86B57C00536FAC11 CRC64;
MDPHWKRHDS SNIPTQPSPS ASPKSNKPSS AQRFGNLPWV APDVIQSQIE YLQALQMQQS
LSESENYLQP NFFPFQSGPF SKSRRENTLL PRLNPLAPIG ARQPNPSIPQ QFSKPINESG
TGTMGPAVGE LTSPVMKNRA ESIFSPVTES FEAFTQGMQT TPQRAGAGVS TATSHTRRRS
SAGTDPFSPV SPSNPNFLTP LKPIDGNQEW QQSPLESPLS MHSLQESLHS VEPESPIFQQ
APQIPLSNAS QQSYINHSSD GASLPQSSFL NFNSSGKRVS VSAAAQQHKN LFLPYLPQAS
LPKFIGTGKL LVGTLHINRK NRSDAYVITD VLDEPIFICG SKDRNRTLEG DLVAVELLDV
NEIMQTKREK EEKKIRRNLS LSGSSKYSVN SKAKMMSIST PMALGMNRGV LSFERSIEKR
KNDYEVTGQS LSFVDDVSLT PDSAPKYAGH VVAVLNRPSG ETCSGTLALY RPNSLALKNQ
SSHRRNSSTS SGETGKGPKI VWFKPSDKRI PLIAISSDQV PPTFFTNNDD FKDKVFLAGI
KRWPTTSLHP FGTLYESIGT IGDPKVEYKA ILHDFSCHTY DFPESLSHCV KRLPTPIPAE
ELQKRYNLRD KLTFMIGTRD YALHIDTGSI DGVITLGIHV ADVAYYVKQD MPLDDEAANR
VSEVQLLQGS VPFLPKKVSE EISLIEGHDC LTISIVVQLD LKSGAVLQCS LGPSVIHPSS
FISLESAQAN LQTNEALQLV DASAHVLTKL RLKTDKKLDL QSLYCFEFCD GQIPNIQNIN
MSIFEAFPIA CSLQQIEHWV NEKVASHLMS VFPSKVILRK NQRPSDFASL VAVSELTGVN
LSASSTPSEI MTEIATTKDK RTKMLLQLTL RRMCNESEYT IGTSNAKDVS HFVFSCPYYT
HFCHPTRRYI DICVQRQLRE AFDGRPDFSK DYRSLLSITQ SCNTLSNFYR NAQEKSLHAY
LCQLLHSINL RSGLVKHKAF VLAVDQEYID IVIYEFGLER RISLDLLPLS NCDFNEQKHE
LYLSWRTNAS FFYASSSLEI DTPCFNDFKK KFLDSNGMCK QICDMMDAQV RDLANAAESQ
ESFYSKARGN DSTSKTAKSS SGNQDISGDG KLHSLRMKEP EVVQTIRPGQ EVSVLIFADT
SATYSLSLIT LQSPLSS
