YBW6_YEAST
ID YBW6_YEAST Reviewed; 175 AA.
AC P38268;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Putative uncharacterized protein YBR116C;
GN OrderedLocusNames=YBR116C; ORFNames=YBR0911;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7900426; DOI=10.1002/yea.320101014;
RA Mannhaupt G., Stucka R., Ehnle S., Vetter I., Feldmann H.;
RT "Analysis of a 70 kb region on the right arm of yeast chromosome II.";
RL Yeast 10:1363-1381(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7813418; DOI=10.1002/j.1460-2075.1994.tb06923.x;
RA Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C.,
RA Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M.,
RA Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M.,
RA Cziepluch C., Demolis N., Delaveau T., Doignon F., Domdey H.,
RA Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D.,
RA Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N.,
RA Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J.,
RA Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C.,
RA Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P.,
RA Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y.,
RA Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F.,
RA Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E.,
RA Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M.,
RA Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B.,
RA Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L.,
RA Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M.,
RA Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S.,
RA Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K.,
RA Mewes H.-W., Kleine K.;
RT "Complete DNA sequence of yeast chromosome II.";
RL EMBO J. 13:5795-5809(1994).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP INDUCTION.
RX PubMed=9845373; DOI=10.1016/s0092-8674(00)81641-4;
RA Holstege F.C.P., Jennings E.G., Wyrick J.J., Lee T.I., Hengartner C.J.,
RA Green M.R., Golub T.R., Lander E.S., Young R.A.;
RT "Dissecting the regulatory circuitry of a eukaryotic genome.";
RL Cell 95:717-728(1998).
RN [6]
RP INDUCTION.
RX PubMed=14561723; DOI=10.1093/jb/mvg155;
RA Sakaki K., Tashiro K., Kuhara S., Mihara K.;
RT "Response of genes associated with mitochondrial function to mild heat
RT stress in yeast Saccharomyces cerevisiae.";
RL J. Biochem. 134:373-384(2003).
RN [7]
RP INDUCTION.
RX PubMed=12414795; DOI=10.1074/jbc.m209759200;
RA Boer V.M., de Winde J.H., Pronk J.T., Piper M.D.W.;
RT "The genome-wide transcriptional responses of Saccharomyces cerevisiae
RT grown on glucose in aerobic chemostat cultures limited for carbon,
RT nitrogen, phosphorus, or sulfur.";
RL J. Biol. Chem. 278:3265-3274(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- INDUCTION: Highly induced during the diauxic shift or during carbon-
CC limited growth, and also induced by mild heat stress.
CC {ECO:0000269|PubMed:12414795, ECO:0000269|PubMed:14561723,
CC ECO:0000269|PubMed:9845373}.
CC -!- MISCELLANEOUS: Partially overlaps TKL2. {ECO:0000305}.
CC -!- CAUTION: Product of a dubious gene prediction unlikely to encode a
CC functional protein. Because of that it is not part of the S.cerevisiae
CC S288c complete/reference proteome set. {ECO:0000305|PubMed:24374639}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X78993; CAA55618.1; -; Genomic_DNA.
DR EMBL; Z35985; CAA85073.1; -; Genomic_DNA.
DR EMBL; AY693259; AAT93278.1; -; Genomic_DNA.
DR PIR; S48280; S48280.
DR AlphaFoldDB; P38268; -.
DR DIP; DIP-2743N; -.
DR IntAct; P38268; 1.
DR MINT; P38268; -.
DR STRING; 4932.YBR116C; -.
DR PaxDb; P38268; -.
DR EnsemblFungi; YBR116C_mRNA; YBR116C; YBR116C.
DR SGD; S000000320; YBR116C.
DR HOGENOM; CLU_1533775_0_0_1; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 5: Uncertain;
KW Membrane; Stress response; Transmembrane; Transmembrane helix.
FT CHAIN 1..175
FT /note="Putative uncharacterized protein YBR116C"
FT /id="PRO_0000202488"
FT TRANSMEM 143..166
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 175 AA; 20215 MW; 6CF72CC0909E055E CRC64;
MQPKNCTILK KSKQELFPCQ TFILLTGKVK NTDSLFYQTV FRSCPLKYWL LQAGVSMLIN
RSDSTNLVVQ ARGLKFTNCS ISQRTVLRQG LKRQSITTKE SSCFLLWEEL SKSEEVNSSL
LFHTSWLMVT CCLKYIYMYD ICTCFLFCAF VTSIFIETDY SIFFLLTASR GIAQF
