YBY7_YEAST
ID YBY7_YEAST Reviewed; 179 AA.
AC P38276; D6VQD3;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 4.
DT 03-AUG-2022, entry version 154.
DE RecName: Full=UPF0303 protein YBR137W;
GN OrderedLocusNames=YBR137W; ORFNames=YBR1013;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8065923; DOI=10.1093/nar/22.15.3104;
RA Kato R., Ogawa H.;
RT "An essential gene, ESR1, is required for mitotic cell growth, DNA repair
RT and meiotic recombination in Saccharomyces cerevisiae.";
RL Nucleic Acids Res. 22:3104-3112(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8091856; DOI=10.1002/yea.320100002;
RA Becam A.-M., Cullin C., Grzybowska E., Lacroute F., Nasr F.,
RA Ozier-Kalogeropoulos O., Palucha A., Slonimski P.P., Zagulski M.,
RA Herbert C.J.;
RT "The sequence of 29.7 kb from the right arm of chromosome II reveals 13
RT complete open reading frames, of which ten correspond to new genes.";
RL Yeast 10:S1-S11(1994).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7813418; DOI=10.1002/j.1460-2075.1994.tb06923.x;
RA Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C.,
RA Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M.,
RA Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M.,
RA Cziepluch C., Demolis N., Delaveau T., Doignon F., Domdey H.,
RA Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D.,
RA Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N.,
RA Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J.,
RA Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C.,
RA Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P.,
RA Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y.,
RA Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F.,
RA Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E.,
RA Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M.,
RA Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B.,
RA Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L.,
RA Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M.,
RA Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S.,
RA Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K.,
RA Mewes H.-W., Kleine K.;
RT "Complete DNA sequence of yeast chromosome II.";
RL EMBO J. 13:5795-5809(1994).
RN [4]
RP GENOME REANNOTATION, AND SEQUENCE REVISION TO 110.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [6]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [7]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-terminal
RT acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 1200 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the UPF0303 family. {ECO:0000305}.
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DR EMBL; D11088; BAA01861.1; -; Genomic_DNA.
DR EMBL; X75891; CAA53495.1; -; Genomic_DNA.
DR EMBL; Z36006; CAA85095.1; -; Genomic_DNA.
DR EMBL; AY558187; AAS56513.1; -; Genomic_DNA.
DR EMBL; BK006936; DAA07253.2; -; Genomic_DNA.
DR PIR; S46006; S46006.
DR RefSeq; NP_009695.2; NM_001178485.2.
DR PDB; 4CLC; X-ray; 2.80 A; A/B/C/D/E=1-179.
DR PDBsum; 4CLC; -.
DR AlphaFoldDB; P38276; -.
DR SMR; P38276; -.
DR BioGRID; 32837; 78.
DR ComplexPortal; CPX-1861; GET4-GET5 transmembrane domain recognition complex.
DR DIP; DIP-2038N; -.
DR IntAct; P38276; 6.
DR MINT; P38276; -.
DR STRING; 4932.YBR137W; -.
DR MaxQB; P38276; -.
DR PaxDb; P38276; -.
DR PRIDE; P38276; -.
DR EnsemblFungi; YBR137W_mRNA; YBR137W; YBR137W.
DR GeneID; 852434; -.
DR KEGG; sce:YBR137W; -.
DR SGD; S000000341; YBR137W.
DR VEuPathDB; FungiDB:YBR137W; -.
DR eggNOG; ENOG502S03S; Eukaryota.
DR HOGENOM; CLU_101036_1_1_1; -.
DR InParanoid; P38276; -.
DR OMA; AWIDRKR; -.
DR BioCyc; YEAST:G3O-29091-MON; -.
DR PRO; PR:P38276; -.
DR Proteomes; UP000002311; Chromosome II.
DR RNAct; P38276; protein.
DR GO; GO:0005737; C:cytoplasm; IDA:SGD.
DR GO; GO:0005829; C:cytosol; IC:ComplexPortal.
DR GO; GO:0072380; C:TRC complex; IDA:SGD.
DR GO; GO:0006620; P:post-translational protein targeting to endoplasmic reticulum membrane; IGI:SGD.
DR Gene3D; 3.30.450.150; -; 1.
DR InterPro; IPR005624; PduO/GlcC-like.
DR InterPro; IPR038084; PduO/GlcC-like_sf.
DR InterPro; IPR010371; UPF0303.
DR PANTHER; PTHR28255; PTHR28255; 1.
DR Pfam; PF03928; Haem_degrading; 1.
DR PIRSF; PIRSF008757; UCP008757; 1.
DR SUPFAM; SSF143744; SSF143744; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Reference proteome.
FT CHAIN 1..179
FT /note="UPF0303 protein YBR137W"
FT /id="PRO_0000208926"
FT CONFLICT 110
FT /note="G -> S (in Ref. 2; CAA53495 and 3; CAA85095)"
FT /evidence="ECO:0000305"
FT HELIX 6..14
FT /evidence="ECO:0007829|PDB:4CLC"
FT HELIX 19..27
FT /evidence="ECO:0007829|PDB:4CLC"
FT STRAND 30..32
FT /evidence="ECO:0007829|PDB:4CLC"
FT HELIX 36..53
FT /evidence="ECO:0007829|PDB:4CLC"
FT STRAND 54..57
FT /evidence="ECO:0007829|PDB:4CLC"
FT STRAND 60..64
FT /evidence="ECO:0007829|PDB:4CLC"
FT STRAND 70..75
FT /evidence="ECO:0007829|PDB:4CLC"
FT HELIX 82..98
FT /evidence="ECO:0007829|PDB:4CLC"
FT HELIX 102..109
FT /evidence="ECO:0007829|PDB:4CLC"
FT TURN 114..116
FT /evidence="ECO:0007829|PDB:4CLC"
FT TURN 122..124
FT /evidence="ECO:0007829|PDB:4CLC"
FT STRAND 131..136
FT /evidence="ECO:0007829|PDB:4CLC"
FT TURN 137..139
FT /evidence="ECO:0007829|PDB:4CLC"
FT STRAND 143..151
FT /evidence="ECO:0007829|PDB:4CLC"
FT HELIX 154..168
FT /evidence="ECO:0007829|PDB:4CLC"
FT TURN 169..172
FT /evidence="ECO:0007829|PDB:4CLC"
SQ SEQUENCE 179 AA; 20454 MW; 8CBA454492E29273 CRC64;
MVVLDKKLLE RLTSRKVPLE ELEDMEKRCF LSTFTYQDAF DLGTYIRNAV KENFPEKPVA
IDISLPNGHC LFRTVTYGGS ALDNDFWIQR KKKTALRFGH SSFYMGCKKG DKTPEEKFFV
DSKEYAFHGG AVLIQSERSD YPYACLTISG LKQEEDHLMA VSSLIAFANE SLEEDLNLD
