ID   YC19_KLEPN              Reviewed;         320 AA.
AC   Q48445;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=UPF0053 protein in cps region;
DE   AltName: Full=ORF19;
DE   Flags: Fragment;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Chedid;
RX   PubMed=7896702; DOI=10.1128/jb.177.7.1788-1796.1995;
RA   Arakawa Y., Wacharotayankun R., Nagatsuka T., Ito H., Kato N., Ohta M.;
RT   "Genomic organization of the Klebsiella pneumoniae cps region responsible
RT   for serotype K2 capsular polysaccharide synthesis in the virulent strain
RT   Chedid.";
RL   J. Bacteriol. 177:1788-1796(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0053 family. {ECO:0000305}.
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DR   EMBL; D21242; BAA21009.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q48445; -.
DR   SMR; Q48445; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR   Gene3D; 3.10.580.10; -; 1.
DR   Gene3D; 3.30.465.10; -; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR044751; Ion_transp-like_CBS.
DR   InterPro; IPR005170; Transptr-assoc_dom.
DR   Pfam; PF00571; CBS; 2.
DR   Pfam; PF03471; CorC_HlyC; 1.
DR   SUPFAM; SSF54631; SSF54631; 1.
DR   SUPFAM; SSF56176; SSF56176; 1.
DR   PROSITE; PS51371; CBS; 2.
PE   3: Inferred from homology;
KW   CBS domain; Cell membrane; Membrane; Repeat; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..>320
FT                   /note="UPF0053 protein in cps region"
FT                   /id="PRO_0000088385"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          121..183
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          186..244
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   NON_TER         320
SQ   SEQUENCE   320 AA;  36282 MW;  23F964B82E058D72 CRC64;
     MILCLSFLLM IGFSLIAEGF SFIIPKGYLY AAIGFSVMIE ALNQLAQFNR RRFLSANMTL
     RQRTTEAVMN LLSGQKEKAE LDADTASLVA DQDQHPLFNP QERLMIERVL NLNQRSVSSI
     MTSRHDIERI NLSAPEEEIR SLVEKNQHTR LVVTGGKDNE DLLGVVHVID LLQQSLRQEP
     LDLQALVRQP LVFPEGLPLL SALEQFRQAR THFAFVVDEF GSVEGIVTLS DVMETIAGNL
     PNEVEEIDAR HDIQHHQDGS WTVNGHMPLE DLVQYVPLPL DDKREYHTVA GLLMEYLQHV
     PQWGRPLRLT VIPCARCRST