YC5C_SCHPO
ID YC5C_SCHPO Reviewed; 491 AA.
AC O94712;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2012, sequence version 2.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Uncharacterized protein C1259.12c;
GN ORFNames=SPCC1259.12c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP REVISION OF GENE MODEL.
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
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DR EMBL; CU329672; CAA22550.2; -; Genomic_DNA.
DR PIR; T40901; T40901.
DR RefSeq; NP_588068.2; NM_001023060.2.
DR AlphaFoldDB; O94712; -.
DR SMR; O94712; -.
DR BioGRID; 275447; 1.
DR STRING; 4896.SPCC1259.12c.1; -.
DR iPTMnet; O94712; -.
DR MaxQB; O94712; -.
DR PaxDb; O94712; -.
DR PRIDE; O94712; -.
DR EnsemblFungi; SPCC1259.12c.1; SPCC1259.12c.1:pep; SPCC1259.12c.
DR GeneID; 2538867; -.
DR KEGG; spo:SPCC1259.12c; -.
DR PomBase; SPCC1259.12c; -.
DR VEuPathDB; FungiDB:SPCC1259.12c; -.
DR eggNOG; KOG1477; Eukaryota.
DR HOGENOM; CLU_009129_0_0_1; -.
DR InParanoid; O94712; -.
DR OMA; VGMKKPG; -.
DR PRO; PR:O94712; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; ISO:PomBase.
DR GO; GO:0034657; C:GID complex; ISO:PomBase.
DR GO; GO:0005634; C:nucleus; ISO:PomBase.
DR GO; GO:0031267; F:small GTPase binding; ISS:PomBase.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0007010; P:cytoskeleton organization; IBA:GO_Central.
DR GO; GO:0045721; P:negative regulation of gluconeogenesis; IC:PomBase.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISO:PomBase.
DR CDD; cd12909; SPRY_RanBP9_10; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR013144; CRA_dom.
DR InterPro; IPR024964; CTLH/CRA.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035782; SPRY_RanBP9/10.
DR Pfam; PF10607; CLTH; 1.
DR Pfam; PF08513; LisH; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00757; CRA; 1.
DR SMART; SM00668; CTLH; 1.
DR SMART; SM00667; LisH; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; SSF49899; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS50896; LISH; 1.
PE 4: Predicted;
KW Reference proteome.
FT CHAIN 1..491
FT /note="Uncharacterized protein C1259.12c"
FT /id="PRO_0000303960"
FT DOMAIN 53..241
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00548"
FT DOMAIN 272..304
FT /note="LisH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00126"
FT DOMAIN 305..362
FT /note="CTLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00058"
SQ SEQUENCE 491 AA; 55963 MW; 0751A8ABED01C6EC CRC64;
MLPRAYLRMT STPKNLEKQP INFDNLPLYL QGTNYGENVL RSDPRWLKWE KYLREFDMTR
EGNVTNTPKA IPSSWNPNDK SDSLELMNNN MGVYFFGPEA GTEHDAASVK ADHAIPSNTS
IYYYEIQILS RGKEGKMGVG FCRKSMQTNR LPGCTAESWG YHGNSGEKFN CSKTGEAYGP
EFTTGDIIGC GVNFINRTIF YTKNGAYLGV AFKKVSDVLY PVIGLKSHGE HVEVNFGQNP
FLYDIDYAIQ MEKNKLFEQA TKSPKQEELK QRQEFLNELI SSFLLNNGFV ETAKKFCPEN
TEVSDASIRK EISSMLANGQ LDLAMTKIDC QYPVAIQECP DLIMSLRFLR FLQLVKVTHD
QRLTKSKGTK QISQEEDLRI LQPLMNYAQE LSNDYEHTKS SNLQAMIKLS MGLLAYFDPF
SSPLSFFMSS DFHKYMAEQI NCLLLELTGH SPDSELRRFL QHTVCLNDLL CRNGCRSNTL
FNVQSDFLSP Y
