YC79_SCHPO
ID YC79_SCHPO Reviewed; 767 AA.
AC O94490;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 115.
DE RecName: Full=Uncharacterized transcriptional regulatory protein C417.09c;
GN ORFNames=SPCC417.09c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00227}; Multi-pass membrane protein {ECO:0000305}.
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DR EMBL; CU329672; CAA22655.1; -; Genomic_DNA.
DR PIR; T41344; T41344.
DR RefSeq; NP_588286.1; NM_001023276.2.
DR AlphaFoldDB; O94490; -.
DR BioGRID; 275539; 13.
DR STRING; 4896.SPCC417.09c.1; -.
DR PaxDb; O94490; -.
DR PRIDE; O94490; -.
DR EnsemblFungi; SPCC417.09c.1; SPCC417.09c.1:pep; SPCC417.09c.
DR GeneID; 2538965; -.
DR KEGG; spo:SPCC417.09c; -.
DR PomBase; SPCC417.09c; -.
DR VEuPathDB; FungiDB:SPCC417.09c; -.
DR eggNOG; ENOG502S0WX; Eukaryota.
DR HOGENOM; CLU_025455_0_0_1; -.
DR InParanoid; O94490; -.
DR OMA; VESAICC; -.
DR PhylomeDB; O94490; -.
DR PRO; PR:O94490; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; NAS:PomBase.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; NAS:PomBase.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00067; GAL4; 1.
DR Gene3D; 4.10.240.10; -; 1.
DR InterPro; IPR007219; Transcription_factor_dom_fun.
DR InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR Pfam; PF04082; Fungal_trans; 1.
DR Pfam; PF00172; Zn_clus; 1.
DR SMART; SM00906; Fungal_trans; 1.
DR SMART; SM00066; GAL4; 1.
DR SUPFAM; SSF57701; SSF57701; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Membrane; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Transmembrane;
KW Transmembrane helix; Zinc.
FT CHAIN 1..767
FT /note="Uncharacterized transcriptional regulatory protein
FT C417.09c"
FT /id="PRO_0000310376"
FT TRANSMEM 328..348
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 601..621
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 629..649
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DNA_BIND 117..143
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 767 AA; 87388 MW; 1E62CEA7A724254F CRC64;
MHARMQPHED RSRSGMSRSE AMELEDQLEE EERGGNVVVG SSSANANAST AETGKKSAGG
SKPKRRRGER IPPSKRIRKA IAYVNKYASG CFGRVERRLV CTRSISRHSN QKLLDFCVEC
KKHKIKCVGN FPCGRCLKKG LECVIETPPR LLMNKDEISL NLQRLSHMET ILSKLMPSMS
LDLPSLEAKI AELSESLQTY PDKVLTDIEL GSYQQVTLNE TQTYYEDAGS NESFVARVHE
IICQGREFQV QHKLTNKGNK TFEDILDPAD NTVASLIHAL PPKDITFYLL MTFWQFSSDN
NHFYYNTKLF AAKVHHLFDD PTSFQSKDGG FVCMLLLSMA MGSLFSYIRH PEFLSDENHD
RWTYPGSQFY QNAKLLFPKV ISESSLETVQ SFFLAGMYLS PTLAHEVVYM YFGIAMRAAV
ANGMHKKSAN AQFSGDVAEL RKRLFWSVYC MERKIGISLG RPESLVRSEI DIHFPEYRES
LDSQNFIASF RTFTLAIKIS LLTNKVYDMW YSSLHGKANL KAATIKEIVN EIEAWRQQLS
PDLEIQNIGP DSRSYRGIVH LHLAYHIVRI AMGRPFLLHR LRERTMNSKT DEGARLLTDK
LISYCYSSAL HIVDLLVLLR MHKFLSVYSF MDYHSCHAAS FIILVHLLIN PSEQTIEQLN
TAIDILNFVT DRFPLLKGST DVITNLRAFA EQSEVYQSRL NATEPAYSTQ VPFFPRDADY
HNQINLQNLW NDENINASLE ALFNDAKGFG FLLPADNFIF PSDDGDM
