YC9F_SCHPO
ID YC9F_SCHPO Reviewed; 594 AA.
AC Q09889; Q9US87;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Arrestin domain-containing protein C584.15c;
GN ORFNames=SPCC584.15c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 267-339.
RC STRAIN=ATCC 38364 / 968;
RX PubMed=10759889; DOI=10.1046/j.1365-2443.2000.00317.x;
RA Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T.,
RA Hiraoka Y.;
RT "Large-scale screening of intracellular protein localization in living
RT fission yeast cells by the use of a GFP-fusion genomic DNA library.";
RL Genes Cells 5:169-190(2000).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-584, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SIMILARITY: Belongs to the arrestin family. {ECO:0000305}.
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DR EMBL; CU329672; CAB37428.1; -; Genomic_DNA.
DR EMBL; AB027970; BAA87274.1; -; Genomic_DNA.
DR PIR; T39135; S62529.
DR RefSeq; NP_588220.1; NM_001023210.2.
DR AlphaFoldDB; Q09889; -.
DR SMR; Q09889; -.
DR BioGRID; 275852; 22.
DR STRING; 4896.SPCC584.15c.1; -.
DR iPTMnet; Q09889; -.
DR MaxQB; Q09889; -.
DR PaxDb; Q09889; -.
DR PRIDE; Q09889; -.
DR EnsemblFungi; SPCC584.15c.1; SPCC584.15c.1:pep; SPCC584.15c.
DR GeneID; 2539284; -.
DR KEGG; spo:SPCC584.15c; -.
DR PomBase; SPCC584.15c; -.
DR VEuPathDB; FungiDB:SPCC584.15c; -.
DR eggNOG; KOG3780; Eukaryota.
DR HOGENOM; CLU_018982_2_0_1; -.
DR InParanoid; Q09889; -.
DR OMA; DLNCIRV; -.
DR PhylomeDB; Q09889; -.
DR Reactome; R-SPO-844456; The NLRP3 inflammasome.
DR PRO; PR:Q09889; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; ISM:PomBase.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; IBA:GO_Central.
DR GO; GO:1990756; F:ubiquitin ligase-substrate adaptor activity; IGI:PomBase.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; ISO:PomBase.
DR GO; GO:0006897; P:endocytosis; IMP:PomBase.
DR GO; GO:0032509; P:endosome transport via multivesicular body sorting pathway; IMP:PomBase.
DR GO; GO:0015031; P:protein transport; IBA:GO_Central.
DR GO; GO:0070086; P:ubiquitin-dependent endocytosis; IBA:GO_Central.
DR Gene3D; 2.60.40.640; -; 1.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR014756; Ig_E-set.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; SSF81296; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..594
FT /note="Arrestin domain-containing protein C584.15c"
FT /id="PRO_0000116541"
FT REGION 368..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..555
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..575
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 584
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 594 AA; 65326 MW; 5011B060E65B29FA CRC64;
MNKIKGGRHK SPVKLFEVRL YNAEANVIVL YGNSMDTSAR LSGIVVLSVS SPIRVKNIKL
RLSGRSFVCW ADESRHASPG NRIRRQVVQI LDKSWSFLAP NESAKVIDQG NYEYPFYYEL
PPDIPDSIEG IPGCHIIYTL TASLERATQP PTNLETALQF RVIRTIPPNS LDLMHSVSVS
DIWPLKVNYE TSIPSKVYAI GSEIPVNITL YPLLKGLDVG KVTLVLKEYC TLFITSKAYS
STCRKEFKRA LVKKTIPGLP MVDDYWQDQI MVKIPDSLGE CTQDCDLNCI RVHHKLRLSI
SLLNPDGHVS ELRNSLPLSL VISPVMFGAR PTEGVFTGDH NSYVNENILP SYDKHVFDVL
WDGIPSENPQ LQSGFTTPNL SRRNSSDFGP NSPVNIHSNP VPISGQQPSS PASNSNANFF
FGSSPQSMSS EQTDMMSPIT SPLAPFSGVT RRAARTRANS ASSVFNSQLQ PLQTDLLSPL
PSPTSSNSRL PRVRSACTLN VQELSKIPPY YEAHSAFTNV LPLDGLPRYE EATRPSSPTE
SVEIPSNTTT IAPSPVPTII APALPSTPAP PLPSHPMATR KSLSSTNLVR RGVR
