YCA2_YEAST
ID YCA2_YEAST Reviewed; 263 AA.
AC P25565; D6VR08; Q8NIM4;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 4.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Putative uncharacterized protein YCL002C;
GN OrderedLocusNames=YCL002C; ORFNames=YCL2C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=1574125; DOI=10.1038/357038a0;
RA Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M.,
RA Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G.,
RA Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A.,
RA Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M., Carcano C.,
RA Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M.,
RA Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C.,
RA Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F.,
RA Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C.,
RA Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E.,
RA Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P.,
RA Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J.,
RA Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P.,
RA Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M.,
RA Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P.,
RA Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G.,
RA Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E.,
RA Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F.,
RA Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L.,
RA Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J.,
RA Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M.,
RA Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A.,
RA Richterich P., Roberts A.B., Rodriguez F., Sanz E.,
RA Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J.,
RA Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I.,
RA Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M.,
RA Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M.,
RA Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D.,
RA Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K.,
RA Sgouros J.G.;
RT "The complete DNA sequence of yeast chromosome III.";
RL Nature 357:38-46(1992).
RN [2]
RP SEQUENCE REVISION.
RA Valles G., Volckaerts G.;
RL Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP GENOME REANNOTATION, AND SEQUENCE REVISION TO 240.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP REVISION OF GENE MODEL.
RX PubMed=12775844; DOI=10.1126/science.1084337;
RA Cliften P.F., Sudarsanam P., Desikan A., Fulton L., Fulton B., Majors J.,
RA Waterston R., Cohen B.A., Johnston M.;
RT "Finding functional features in Saccharomyces genomes by phylogenetic
RT footprinting.";
RL Science 301:71-76(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAC42967.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAC42967.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X59720; CAC42967.1; ALT_SEQ; Genomic_DNA.
DR EMBL; BK006937; DAA07477.2; -; Genomic_DNA.
DR PIR; S19357; S19357.
DR RefSeq; NP_009924.4; NM_001178652.2.
DR AlphaFoldDB; P25565; -.
DR BioGRID; 30976; 92.
DR IntAct; P25565; 1.
DR PaxDb; P25565; -.
DR PRIDE; P25565; -.
DR EnsemblFungi; YCL002C_mRNA; YCL002C; YCL002C.
DR GeneID; 850353; -.
DR KEGG; sce:YCL002C; -.
DR SGD; S000000508; YCL002C.
DR VEuPathDB; FungiDB:YCL002C; -.
DR eggNOG; ENOG502RXGR; Eukaryota.
DR HOGENOM; CLU_095775_0_0_1; -.
DR InParanoid; P25565; -.
DR OMA; GKFGIFY; -.
DR BioCyc; YEAST:G3O-29276-MON; -.
DR PRO; PR:P25565; -.
DR Proteomes; UP000002311; Chromosome III.
DR RNAct; P25565; protein.
DR GO; GO:0005829; C:cytosol; HDA:SGD.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
PE 4: Predicted;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..263
FT /note="Putative uncharacterized protein YCL002C"
FT /id="PRO_0000202537"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 230..250
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 263 AA; 30197 MW; E8ED84B6D9EA7BF0 CRC64;
MLVIVLQGLA GFLSIIAILC QKRYNKLHRS IYGLSYDLFL LDFVGNGLYL YCALHYCYSS
LVREQLSQRF PLFYPLNDAR SIPISSFLIL KDFCVSCCCM MVLRQLYYYR STKHIYQGIS
ITSIIIISVF LVLGIFTYGC SISNLPLKNS GKFGVFYLEH INYLWVMANL LKCFKYVPQM
SINWMGCSTV GLSSKFALIS FLAESIDLLG RLVIPTNALF YEIPFNSTPF WVKLIQFVTL
LVILCQVQYV YVGRKPRLPK GKL
