YCAC_ECOLI
ID YCAC_ECOLI Reviewed; 208 AA.
AC P21367;
DT 01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1991, sequence version 1.
DT 03-AUG-2022, entry version 143.
DE RecName: Full=Probable hydrolase YcaC;
DE EC=4.-.-.-;
GN Name=ycaC; OrderedLocusNames=b0897, JW0880;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / C600 / CR34 / ATCC 23724 / DSM 3925 / LMG 3041 / NCIB 10222;
RX PubMed=3062312; DOI=10.1111/j.1365-2958.1988.tb00090.x;
RA Bilous P.T., Cole S.T., Anderson W.F., Weiner J.H.;
RT "Nucleotide sequence of the dmsABC operon encoding the anaerobic
RT dimethylsulphoxide reductase of Escherichia coli.";
RL Mol. Microbiol. 2:785-795(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS), AND SUBUNIT.
RX PubMed=9782055; DOI=10.1016/s0969-2126(98)00132-4;
RA Colovos C., Cascio D., Yeates T.O.;
RT "The 1.8-A crystal structure of the ycaC gene product from Escherichia coli
RT reveals an octameric hydrolase of unknown specificity.";
RL Structure 6:1329-1337(1998).
CC -!- SUBUNIT: Homooctamer composed of two tetrameric rings.
CC {ECO:0000269|PubMed:9782055}.
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DR EMBL; J03412; AAA83846.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73983.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35629.1; -; Genomic_DNA.
DR PIR; S09671; S09671.
DR RefSeq; NP_415417.1; NC_000913.3.
DR RefSeq; WP_000165879.1; NZ_SSZK01000002.1.
DR PDB; 1YAC; X-ray; 1.80 A; A/B=1-208.
DR PDBsum; 1YAC; -.
DR AlphaFoldDB; P21367; -.
DR SMR; P21367; -.
DR BioGRID; 4259587; 15.
DR BioGRID; 849886; 1.
DR DIP; DIP-11462N; -.
DR IntAct; P21367; 5.
DR STRING; 511145.b0897; -.
DR jPOST; P21367; -.
DR PaxDb; P21367; -.
DR PRIDE; P21367; -.
DR EnsemblBacteria; AAC73983; AAC73983; b0897.
DR EnsemblBacteria; BAA35629; BAA35629; BAA35629.
DR GeneID; 945512; -.
DR KEGG; ecj:JW0880; -.
DR KEGG; eco:b0897; -.
DR PATRIC; fig|1411691.4.peg.1380; -.
DR EchoBASE; EB1223; -.
DR eggNOG; COG1335; Bacteria.
DR HOGENOM; CLU_066901_1_2_6; -.
DR InParanoid; P21367; -.
DR OMA; SNDRMRD; -.
DR PhylomeDB; P21367; -.
DR BioCyc; EcoCyc:EG11241-MON; -.
DR EvolutionaryTrace; P21367; -.
DR PRO; PR:P21367; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005829; C:cytosol; HDA:UniProtKB.
DR GO; GO:0016020; C:membrane; HDA:UniProtKB.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IDA:EcoCyc.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.850; -; 1.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF52499; SSF52499; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Hydrolase; Lyase; Reference proteome.
FT CHAIN 1..208
FT /note="Probable hydrolase YcaC"
FT /id="PRO_0000168753"
FT ACT_SITE 118
FT /evidence="ECO:0000255"
FT STRAND 12..18
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 24..27
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 33..49
FT /evidence="ECO:0007829|PDB:1YAC"
FT STRAND 54..60
FT /evidence="ECO:0007829|PDB:1YAC"
FT TURN 61..65
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 70..75
FT /evidence="ECO:0007829|PDB:1YAC"
FT STRAND 81..86
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 90..92
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 94..102
FT /evidence="ECO:0007829|PDB:1YAC"
FT STRAND 106..114
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 115..119
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 120..128
FT /evidence="ECO:0007829|PDB:1YAC"
FT STRAND 132..136
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 145..158
FT /evidence="ECO:0007829|PDB:1YAC"
FT STRAND 161..163
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 165..173
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 176..178
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 180..190
FT /evidence="ECO:0007829|PDB:1YAC"
FT HELIX 192..204
FT /evidence="ECO:0007829|PDB:1YAC"
SQ SEQUENCE 208 AA; 23100 MW; 5FB5A4F0CC049BEB CRC64;
MTKPYVRLDK NDAAVLLVDH QAGLLSLVRD IEPDKFKNNV LALGDLAKYF NLPTILTTSF
ETGPNGPLVP ELKAQFPDTP YIARPGNINA WDNEDFVKAV KATGKKQLII AGVVTEVCVA
FPALSAIEEG FDVFVVTDAS GTFNEITRHS AWDRLSQAGA QLMTWFGVAC ELHRDWRNDI
EGLATLFSNH IPDYRNLMTS YDTLTKQK
