ID   YCAD_SALA4              Reviewed;         382 AA.
AC   B5F150;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Uncharacterized MFS-type transporter YcaD {ECO:0000255|HAMAP-Rule:MF_01149};
GN   Name=ycaD {ECO:0000255|HAMAP-Rule:MF_01149}; OrderedLocusNames=SeAg_B0972;
OS   Salmonella agona (strain SL483).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=454166;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL483;
RX   PubMed=21602358; DOI=10.1128/jb.00297-11;
RA   Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA   Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT   CRISPR-mediated adaptive sublineage evolution.";
RL   J. Bacteriol. 193:3556-3568(2011).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01149}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01149}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. YcaD (TC
CC       2.A.1.26) family. {ECO:0000255|HAMAP-Rule:MF_01149}.
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DR   EMBL; CP001138; ACH52606.1; -; Genomic_DNA.
DR   RefSeq; WP_000109274.1; NC_011149.1.
DR   AlphaFoldDB; B5F150; -.
DR   SMR; B5F150; -.
DR   EnsemblBacteria; ACH52606; ACH52606; SeAg_B0972.
DR   KEGG; sea:SeAg_B0972; -.
DR   HOGENOM; CLU_035018_1_2_6; -.
DR   OMA; IGIGDHM; -.
DR   Proteomes; UP000008819; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   HAMAP; MF_01149; MFS_YcaD; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR023745; MFS_YcaD.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..382
FT                   /note="Uncharacterized MFS-type transporter YcaD"
FT                   /id="PRO_1000137492"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        75..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        325..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
SQ   SEQUENCE   382 AA;  41578 MW;  76E74E108EF170EA CRC64;
     MSTYTRPVML LLCGLLLLTL AIAVLNTLVP LWLAQANLPT WQVGMVSSSY FTGNLVGTLF
     TGYLIKRIGF NRSYYLASLI FAAGCVGLGV MVGFWSWMSW RFIAGIGCAM IWVVVESALM
     CSGTSHNRGR LLAAYMMVYY MGTFLGQLLV SKVSGELLHV LPWVTGMILA GILPLLFTRI
     VNQQTQTRHS SSISAMLKLR QARLGVNGCI ISGIVLGSLY GLMPLYLKHQ GMANASIGFW
     MAVLVSAGIL GQWPMGRLAD KFGRLLVLRV QVFVVILGSI AMLTQAAMAP ALFILGAAGF
     TLYPVAMAWA CEKVEHHQLV AMNQALLLSY TVGSLLGPSF AAMLMQNYSD NLLFIMIASV
     SFIYLLMLLR NAGQTPNPVA HI