YCAD_SALEP
ID YCAD_SALEP Reviewed; 382 AA.
AC B5QYP8;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 04-NOV-2008, sequence version 1.
DT 25-MAY-2022, entry version 65.
DE RecName: Full=Uncharacterized MFS-type transporter YcaD {ECO:0000255|HAMAP-Rule:MF_01149};
GN Name=ycaD {ECO:0000255|HAMAP-Rule:MF_01149}; OrderedLocusNames=SEN0872;
OS Salmonella enteritidis PT4 (strain P125109).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=550537;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P125109;
RX PubMed=18583645; DOI=10.1101/gr.077404.108;
RA Thomson N.R., Clayton D.J., Windhorst D., Vernikos G., Davidson S.,
RA Churcher C., Quail M.A., Stevens M., Jones M.A., Watson M., Barron A.,
RA Layton A., Pickard D., Kingsley R.A., Bignell A., Clark L., Harris B.,
RA Ormond D., Abdellah Z., Brooks K., Cherevach I., Chillingworth T.,
RA Woodward J., Norberczak H., Lord A., Arrowsmith C., Jagels K., Moule S.,
RA Mungall K., Saunders M., Whitehead S., Chabalgoity J.A., Maskell D.,
RA Humphreys T., Roberts M., Barrow P.A., Dougan G., Parkhill J.;
RT "Comparative genome analysis of Salmonella enteritidis PT4 and Salmonella
RT gallinarum 287/91 provides insights into evolutionary and host adaptation
RT pathways.";
RL Genome Res. 18:1624-1637(2008).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01149}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01149}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. YcaD (TC
CC 2.A.1.26) family. {ECO:0000255|HAMAP-Rule:MF_01149}.
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DR EMBL; AM933172; CAR32455.1; -; Genomic_DNA.
DR RefSeq; WP_000109268.1; NC_011294.1.
DR AlphaFoldDB; B5QYP8; -.
DR SMR; B5QYP8; -.
DR KEGG; set:SEN0872; -.
DR HOGENOM; CLU_035018_1_2_6; -.
DR OMA; IGIGDHM; -.
DR Proteomes; UP000000613; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1250.20; -; 2.
DR HAMAP; MF_01149; MFS_YcaD; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR023745; MFS_YcaD.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..382
FT /note="Uncharacterized MFS-type transporter YcaD"
FT /id="PRO_1000137494"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
SQ SEQUENCE 382 AA; 41520 MW; 1E465E1DE5B983AE CRC64;
MSTYTRPVML LLCGLLLLTL AIAVLNTLVP LWLAQANLPT WQVGMVSSSY FTGNLVGTLF
TGYLIKRIGF NRSYYLASLI FAAGCVGLGV MVGFWSWMSW RFIAGIGCAM IWVVVESALM
CSGTSHNRGR LLAAYMMAYY MGTFLGQLLV SKVSGELLHV LPWVTGMILA GILPLLFTRI
VNQQTQARHS SSISAMLKLR QARLGVNGCI ISGIVLGSLY GLMPLYLKHQ GMANASIGFW
MAVLVSAGIL GQWPMGRLAD KFGRLLVLRV QVFVVILGSI AMLTQAAMAP ALFILGAAGF
TLYPVAMAWA CEKVEHHQLV AMNQALLLSY TVGSLLGPSF AAMLMQNYSD NLLFIMIASV
SFIYLLMLLR NAGQTPNPVA HI