ID   YCAD_SALG2              Reviewed;         382 AA.
AC   B5R8I5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   04-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Uncharacterized MFS-type transporter YcaD {ECO:0000255|HAMAP-Rule:MF_01149};
GN   Name=ycaD {ECO:0000255|HAMAP-Rule:MF_01149}; OrderedLocusNames=SG0910;
OS   Salmonella gallinarum (strain 287/91 / NCTC 13346).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=550538;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=287/91 / NCTC 13346;
RX   PubMed=18583645; DOI=10.1101/gr.077404.108;
RA   Thomson N.R., Clayton D.J., Windhorst D., Vernikos G., Davidson S.,
RA   Churcher C., Quail M.A., Stevens M., Jones M.A., Watson M., Barron A.,
RA   Layton A., Pickard D., Kingsley R.A., Bignell A., Clark L., Harris B.,
RA   Ormond D., Abdellah Z., Brooks K., Cherevach I., Chillingworth T.,
RA   Woodward J., Norberczak H., Lord A., Arrowsmith C., Jagels K., Moule S.,
RA   Mungall K., Saunders M., Whitehead S., Chabalgoity J.A., Maskell D.,
RA   Humphreys T., Roberts M., Barrow P.A., Dougan G., Parkhill J.;
RT   "Comparative genome analysis of Salmonella enteritidis PT4 and Salmonella
RT   gallinarum 287/91 provides insights into evolutionary and host adaptation
RT   pathways.";
RL   Genome Res. 18:1624-1637(2008).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01149}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01149}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. YcaD (TC
CC       2.A.1.26) family. {ECO:0000255|HAMAP-Rule:MF_01149}.
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DR   EMBL; AM933173; CAR36800.1; -; Genomic_DNA.
DR   RefSeq; WP_000109265.1; NC_011274.1.
DR   AlphaFoldDB; B5R8I5; -.
DR   SMR; B5R8I5; -.
DR   EnsemblBacteria; CAR36800; CAR36800; SG0910.
DR   KEGG; seg:SG0910; -.
DR   HOGENOM; CLU_035018_1_2_6; -.
DR   OMA; IGIGDHM; -.
DR   Proteomes; UP000008321; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   HAMAP; MF_01149; MFS_YcaD; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR023745; MFS_YcaD.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..382
FT                   /note="Uncharacterized MFS-type transporter YcaD"
FT                   /id="PRO_1000137495"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        75..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        274..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        325..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
SQ   SEQUENCE   382 AA;  41505 MW;  56BE5D4F5572E365 CRC64;
     MSTYTRPVML LLCGLLLLTL AIAVLNTLVP LWLAQANLPT WQVGMVSSSY FTGNLVGTLF
     TGYLIKRIGF NRSYYLASLI FAAGCVGLGG MVGFWSWMSW RFIAGIGCAM IWVVVESALM
     CSGTSHNRGR LLAAYMMAYY MGTFLGQLLV SKVSGELLHV LPWVTGMILA GILPLLFTRI
     VNQQTQARHS SSISAMLKLR QARLGVNGCI ISGIVLGSLY GLMPLYLKHQ GMANASIGFW
     MAVLVSAGIL GQWPMGRLAD KFGRLLVLRV QVFVVILGSI AMLTQAAMAP ALFILGAAGF
     KLYPVAMAWA CEKVEHHQLV AMNQALLLSY TVGSLLGPSF AAMLMQNYSD NLLFIMIASV
     SFIYLLMLLR NAGQTPNPVA HI