YCAD_SALTY
ID YCAD_SALTY Reviewed; 382 AA.
AC Q8ZQD2;
DT 26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Uncharacterized MFS-type transporter YcaD;
GN Name=ycaD; OrderedLocusNames=STM0968;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. YcaD (TC
CC 2.A.1.26) family. {ECO:0000305}.
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DR EMBL; AE006468; AAL19902.1; -; Genomic_DNA.
DR RefSeq; NP_459943.1; NC_003197.2.
DR RefSeq; WP_000109271.1; NC_003197.2.
DR AlphaFoldDB; Q8ZQD2; -.
DR SMR; Q8ZQD2; -.
DR STRING; 99287.STM0968; -.
DR PaxDb; Q8ZQD2; -.
DR EnsemblBacteria; AAL19902; AAL19902; STM0968.
DR GeneID; 1252486; -.
DR KEGG; stm:STM0968; -.
DR PATRIC; fig|99287.12.peg.1020; -.
DR HOGENOM; CLU_035018_1_2_6; -.
DR OMA; IGIGDHM; -.
DR PhylomeDB; Q8ZQD2; -.
DR BioCyc; SENT99287:STM0968-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1250.20; -; 2.
DR HAMAP; MF_01149; MFS_YcaD; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR023745; MFS_YcaD.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..382
FT /note="Uncharacterized MFS-type transporter YcaD"
FT /id="PRO_0000084893"
FT TOPO_DOM 1..7
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 29..44
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 66..74
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 96..101
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 123..130
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 152..156
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 178..203
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 225..230
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 252..269
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 312..324
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 346..348
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 370..382
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 382 AA; 41548 MW; 26565E1DE38D11E7 CRC64;
MSTYTRPVML LLCGLLLLTL AIAVLNTLVP LWLAQANLPT WQVGMVSSSY FTGNLVGTLF
TGYLIKRIGF NRSYYLASLI FAAGCVGLGV MVGFWSWMSW RFIAGIGCAM IWVVVESALM
CSGTSHNRGR LLAAYMMVYY MGTFLGQLLV SKVSGELLHV LPWVTGMILA GILPLLFTRI
VNQQTQARHS SSISAMLKLR QARLGVNGCI ISGIVLGSLY GLMPLYLKHQ GMANASIGFW
MAVLVSAGIL GQWPMGRLAD KFGRLLVLRV QVFVVILGSI AMLTQAAMAP ALFILGAAGF
TLYPVAMAWA CEKVEHHQLV AMNQALLLSY TVGSLLGPSF AAMLMQNYSD NLLFIMIASV
SFIYLLMLLR NAGQTPNPVA HI
