YCAI_ECOLI
ID YCAI_ECOLI Reviewed; 754 AA.
AC P37443; P75841;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 27-APR-2001, sequence version 3.
DT 03-AUG-2022, entry version 151.
DE RecName: Full=Uncharacterized protein YcaI;
GN Name=ycaI; OrderedLocusNames=b0913, JW5120;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 581-754.
RC STRAIN=K12;
RX PubMed=8094880; DOI=10.1111/j.1365-2958.1993.tb01098.x;
RA Karow M.L., Georgopoulos C.;
RT "The essential Escherichia coli msbA gene, a multicopy suppressor of null
RT mutations in the htrB gene, is related to the universally conserved family
RT of ATP-dependent translocators.";
RL Mol. Microbiol. 7:69-79(1993).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: To B.subtilis ComEC, N.gonorrhoeae ComA, and H.influenzae
CC Rec2. {ECO:0000305}.
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DR EMBL; U00096; AAC73999.2; -; Genomic_DNA.
DR EMBL; AP009048; BAA35657.2; -; Genomic_DNA.
DR EMBL; Z11796; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; H64830; H64830.
DR RefSeq; NP_415433.4; NC_000913.3.
DR RefSeq; WP_000705764.1; NZ_SSZK01000002.1.
DR AlphaFoldDB; P37443; -.
DR BioGRID; 4261065; 133.
DR STRING; 511145.b0913; -.
DR PaxDb; P37443; -.
DR PRIDE; P37443; -.
DR EnsemblBacteria; AAC73999; AAC73999; b0913.
DR EnsemblBacteria; BAA35657; BAA35657; BAA35657.
DR GeneID; 945531; -.
DR KEGG; ecj:JW5120; -.
DR KEGG; eco:b0913; -.
DR PATRIC; fig|1411691.4.peg.1363; -.
DR EchoBASE; EB2278; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR HOGENOM; CLU_010363_3_0_6; -.
DR InParanoid; P37443; -.
DR OMA; RTDKQGA; -.
DR PhylomeDB; P37443; -.
DR BioCyc; EcoCyc:EG12375-MON; -.
DR PRO; PR:P37443; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; -; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; SSF56281; 1.
DR TIGRFAMs; TIGR00360; ComEC_N-term; 1.
DR TIGRFAMs; TIGR00361; ComEC_Rec2; 1.
PE 4: Predicted;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..754
FT /note="Uncharacterized protein YcaI"
FT /id="PRO_0000168754"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 320..340
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 370..390
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 392..412
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 446..466
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 471..491
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 581..595
FT /note="PLNWEHHQPCVRGEA -> SVKLGTSSALCAWRT (in Ref. 4;
FT Z11796)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 754 AA; 84474 MW; C3423D13889AF170 CRC64;
MKITTVGVCI ISGIFPLLIL PQLPGTLTLA FLTLFACVLA FIPVKTVRYI ALTLLFFVWG
ILSAKQILWA GETLTGATQD AIVEITATDG MTTHYGQITH LQGRRIFPAS GLVMYGEYLP
QAVCAGQQWS MKLKVRAVHG QLNDGGFDSQ RYAIAQHQPL TGRFLQASVI EPNCSLRAQY
LASLQTTLQP YPWNAVILGL GMGERLSVPK EIKNIMRDTG TAHLMAISGL HIAFAALLAA
GLIRSGQIFL PGRWIHWQIP LIGGICCAAF YAWLTGMQPP ALRTMVALAT WGMLKLSGRQ
WSGWDVWICC LAAILLMDPV AILSQSLWLS AAAVAALIFW YQWFPCPEWQ LPPVLRAVVS
LIHLQLGITL LLMPVQIVIF HGISLTSFIA NLLAIPLVTF ITVPLILAAM VVHLSGPLIL
EQGLWFLADR SLALLFWGLK SLPEGWINIA ECWQWLSFSP WFLLVVWRLN AWRTLPAMCV
AGGLLMCWPL WQKPRPDEWQ LYMLDVGQGL AMVIARNGKA ILYDTGLAWP EGDSGQQLII
PWLHWHNLEP EGVILSHEHL DHRGGLDSIL HIWPMLWIRS PLNWEHHQPC VRGEAWQWQG
LRFSAHWPLQ GSNDKGNNHS CVVKVDDGTN SILLTGDIEA PAEQKMLSRY WQQVQATLLQ
VPHHGSNTSS SLPLIQRVNG KVALASASRY NAWRLPSNKV KHRYQLQGYQ WIDTPHQGQT
TVNFSAQGWR ISSLREQILP RWYHQWFGVP VDNG
