ID   YCAK_ECOLI              Reviewed;         196 AA.
AC   P43340; P75837;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Uncharacterized NAD(P)H oxidoreductase YcaK;
DE            EC=1.6.99.-;
GN   Name=ycaK; OrderedLocusNames=b0901, JW0884;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 133-196.
RC   STRAIN=K12;
RX   PubMed=3053170; DOI=10.1111/j.1432-1033.1988.tb14356.x;
RA   Roedel W., Plaga W., Frank R., Knappe J.;
RT   "Primary structures of Escherichia coli pyruvate formate-lyase and
RT   pyruvate-formate-lyase-activating enzyme deduced from the DNA nucleotide
RT   sequences.";
RL   Eur. J. Biochem. 177:153-158(1988).
RN   [5]
RP   IDENTIFICATION.
RX   PubMed=7567469; DOI=10.1093/nar/23.17.3554;
RA   Borodovsky M., McIninch J., Koonin E.V., Rudd K.E., Medigue C., Danchin A.;
RT   "Detection of new genes in a bacterial genome using Markov models for three
RT   gene classes.";
RL   Nucleic Acids Res. 23:3554-3562(1995).
CC   -!- SIMILARITY: Belongs to the NAD(P)H dehydrogenase (quinone) family.
CC       {ECO:0000305}.
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DR   EMBL; U00096; AAC73987.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA35636.1; -; Genomic_DNA.
DR   EMBL; X08035; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; D64829; D64829.
DR   RefSeq; NP_415421.1; NC_000913.3.
DR   RefSeq; WP_001190363.1; NZ_STEB01000006.1.
DR   AlphaFoldDB; P43340; -.
DR   SMR; P43340; -.
DR   BioGRID; 4260008; 15.
DR   IntAct; P43340; 4.
DR   STRING; 511145.b0901; -.
DR   jPOST; P43340; -.
DR   PaxDb; P43340; -.
DR   PRIDE; P43340; -.
DR   EnsemblBacteria; AAC73987; AAC73987; b0901.
DR   EnsemblBacteria; BAA35636; BAA35636; BAA35636.
DR   GeneID; 945520; -.
DR   KEGG; ecj:JW0884; -.
DR   KEGG; eco:b0901; -.
DR   PATRIC; fig|511145.12.peg.932; -.
DR   EchoBASE; EB2564; -.
DR   eggNOG; COG2249; Bacteria.
DR   HOGENOM; CLU_058643_1_1_6; -.
DR   InParanoid; P43340; -.
DR   OMA; VYPLWWM; -.
DR   PhylomeDB; P43340; -.
DR   BioCyc; EcoCyc:EG12702-MON; -.
DR   PRO; PR:P43340; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0010181; F:FMN binding; IDA:EcoCyc.
DR   GO; GO:0003955; F:NAD(P)H dehydrogenase (quinone) activity; IBA:GO_Central.
DR   Gene3D; 3.40.50.360; -; 1.
DR   InterPro; IPR003680; Flavodoxin_fold.
DR   InterPro; IPR029039; Flavoprotein-like_sf.
DR   Pfam; PF02525; Flavodoxin_2; 1.
DR   SUPFAM; SSF52218; SSF52218; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..196
FT                   /note="Uncharacterized NAD(P)H oxidoreductase YcaK"
FT                   /id="PRO_0000071630"
SQ   SEQUENCE   196 AA;  23036 MW;  4592F20BD4F8BA90 CRC64;
     MQSERIYLVW AHPRHDSLTA HIADAIHQRA MERKIQVTEL DLYRRNFNPV MTPEDEPDWK
     NMDKRYSPEV HQLYSELLEH DTLVVVFPLW WYSFPAMLKG YIDRVWNNGL AYGDGHKLPF
     NKVRWVALVG GDKESFVQMG WEKNISDYLK NMCSYLGIED ADVTFLCNTV VFDGEELHAS
     YYQSLLSQVR DMVDAL