ID   YCAN_ECOLI              Reviewed;         302 AA.
AC   P75836;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 139.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YcaN;
GN   Name=ycaN; OrderedLocusNames=b0900, JW0883;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U00096; AAC73986.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA35635.1; -; Genomic_DNA.
DR   PIR; C64829; C64829.
DR   RefSeq; NP_415420.1; NC_000913.3.
DR   RefSeq; WP_001242684.1; NZ_SSZK01000002.1.
DR   AlphaFoldDB; P75836; -.
DR   SMR; P75836; -.
DR   BioGRID; 4261671; 17.
DR   STRING; 511145.b0900; -.
DR   PaxDb; P75836; -.
DR   PRIDE; P75836; -.
DR   DNASU; 945523; -.
DR   EnsemblBacteria; AAC73986; AAC73986; b0900.
DR   EnsemblBacteria; BAA35635; BAA35635; BAA35635.
DR   GeneID; 945523; -.
DR   KEGG; ecj:JW0883; -.
DR   KEGG; eco:b0900; -.
DR   PATRIC; fig|1411691.4.peg.1376; -.
DR   EchoBASE; EB3462; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_16_1_6; -.
DR   InParanoid; P75836; -.
DR   OMA; DEANCFR; -.
DR   PhylomeDB; P75836; -.
DR   BioCyc; EcoCyc:G6467-MON; -.
DR   PRO; PR:P75836; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006351; P:transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..302
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YcaN"
FT                   /id="PRO_0000105781"
FT   DOMAIN          1..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        20..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   302 AA;  34294 MW;  8FFF02FB02B24B73 CRC64;
     MRMNMSDFAT FFAVARNQSF RAAGDELGLS SSAISHSIKT LEQRLKIRLF NRTTRSVSLT
     EAGSNLYERL RPAFDEIQIM LDEMNDFRLT PTGTLKINAA RVAARIFLMS LLVGFTREYP
     DIKVELTTDD SLVDIVQQGF DAGVRLSCIV EKDMISVAIG PPVKLCVAAT PEYFARYGKP
     RHPHDLLNHQ CVVFRYPSGK PFHWQFAKEL EIAVAGNIIL DDVDAELEAV LMGAGIGYLL
     YEQIKEYLDT GRLECVLEDW STERPGFQIY YPNRQYMSCG LRAFLDYVKT GQICQSQRHR
     PQ